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ProteomicsIdentification of regulators of polyploidization presents therapeutic targetsfor treatment of AMKL
Wen Q, Goldenson B, Silver SJ, Schenone M, Dancik V, Huang Z, Wang LZ, Lewis TA, An WF, Li X, Bray MA, Thiollier C, Diebold L, Gilles L, Vokes MS, Moore CB, Bliss-Moreau M, Verplank L, Tolliday NJ, Mishra R, Vemula S, Shi J, Wei L, Kapur R, Lopez CK, Gerby B, Ballerini P, Pflumio F, Gilliland DG, Go...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2014-01-27 | MSV000078536 | MassIVE
MetabolomicsDivergent relationships between faecal microbiota and metabolome following distinct antibiotic-induced disruptions
The intestinal microbiome plays an essential role in regulating many aspects of host physiology, and its disruption through antibiotic exposure has been implicated in the development of a range of serious pathologies. The complex metabolic relationships that exist between members of the intestinal m...
2017-03-03 | MTBLS422 | MetaboLights
UnknownThe genetic association of the transcription factor NPAT with glycemic response to metformin involves regulation of fuel selection.
Not available
S-EPMC8248654 | biostudies-literature
UnknownCSF-resident CD4<sup>+</sup> T-cells display a distinct gene expression profile with relevance to immune surveillance and multiple sclerosis.
Not available
S-EPMC8574295 | biostudies-literature
UnknownIL-15 and PIM kinases direct the metabolic programming of intestinal intraepithelial lymphocytes.
Not available
S-EPMC8277781 | biostudies-literature
UnknownAssociations between stroke mortality and weekend working by stroke specialist physicians and registered nurses: prospective multicentre cohort study.
Not available
S-EPMC4138029 | biostudies-literature
MetabolomicsFour Weeks of Probiotic Supplementation Alters the Metabolic Perturbations Induced by Marathon Running: Insight from Metabolomics
Few data are available that describe how probiotics influence systemic metabolism during endurance exercise. Metabolomic profiling of endurance athletes will elucidate mechanisms by which probiotics may confer benefits to the athlete. In this study, twenty-four runners (20 male, 4 female) were block...
2021-09-03 | MTBLS1357 | MetaboLights
ProteomicsComprehensive proteomics analyses of IL-15 driven activation of intestinal intraepithelial lymphocytes
Intestinal intraepithelial lymphocytes (IEL) are an abundant population of tissue-resident T cells that protect the gut from pathogens and maintain intestinal homeostasis. The cytokine IL-15 is trans-presented by epithelial cells to IEL in complex with the IL-15 receptor α chain (IL-15Rα) and plays ...
ORGANISM(S): Mus musculus (Mouse) 
2021-05-10 | PXD025891 | Pride
Intraepithelial lymphocytes  interleukin-15  quantitative proteomics  coeliac disease  histone ruler  lfq 
UnknownMAGE-A Cancer/Testis Antigens Inhibit MDM2 Ubiquitylation Function and Promote Increased Levels of MDM4.
Not available
S-EPMC4441487 | biostudies-literature
TranscriptomicsRNA-seq comparison of fetal lung and cultured fetal lung derived organoids with pluripotent stem cell derived lung organoids
Underdeveloped lungs are the primary cause of death in premature infants, however, little is known about stem and progenitor cell maintenance during human lung development. In this study, we have identified that FGF7, Retinoic Acid and CHIR-99021, a small molecule that inhibits GSK3 to activate Wnt ...
ORGANISM(S): Homo sapiens 
2018-11-17 | E-MTAB-6023 | biostudies-arrayexpress
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