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ProteomicsThe COMPASS subunit Bre2 targets CRF Arp9 to regulate the bio-synthesis of secondary metabolite AFB1 and virulence in Aspergillus flavus
Aspergillus flavus, along with its notorious secondary metabolite aflatoxin B1 (AFB1), serious endangers human health. We previous revealed that histone methyltransferase complex COMPASS plays a crucial role in regulating various biological processes of A. flavus, but underlying mechanism is unclear...
ORGANISM(S): Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / NRRL 3357 / JCM 12722 / SRRC 167) 
2026-02-08 | PXD060646 | Pride
Aspergillus flavus Histone methyltransferase Arp9 Chromatin remolding factor Bre2 
GenomicsThe COMPASS subunit Bre2 targets CRF Arp9 to regulate the bio-synthesis of secondary metabolite AFB1 and virulence in Aspergillus flavus
In this study, To determine the chromatin distribution pattern of Bre2-regulated H3K4me3 at the genome-wide level, we used the BRE2 knockout strain constructed in this study as a control; Chip-sequencing (ChIP-seq) experiments were performed in WT strains using an antibody to H3K4me3 to search for t...
ORGANISM(S): Aspergillus flavus 
2026-02-02 | GSE285749 | GEO
GenomicsThe COMPASS subunit Bre2 targets CRF Arp9 to regulate the bio-synthesis of secondary metabolite AFB1 and virulence in Aspergillus flavus
The COMPASS subunit Bre2 targets CRF Arp9 to regulate the bio-synthesis of secondary metabolite AFB1 and virulence in Aspergillus flavus
PRJNA1205754 | ENA
UnknownCOMPASS subunit Bre2 regulates chromatin remodeler Arp9 to control Aspergillus flavus aflatoxin synthesis and virulence.
Not available
S-EPMC12923686 | biostudies-literature
UnknownA conserved interaction between the SDI domain of Bre2 and the Dpy-30 domain of Sdc1 is required for histone methylation and gene expression.
Not available
S-EPMC2804208 | biostudies-literature
GenomicsThe COMPASS subunit Bre2 targets CRF Arp9 to regulate the bio-synthesis of secondary metabolite AFB1 and virulence in Aspergillus flavus [ATAC-seq]
Aspergillus flavus, along with its notorious secondary metabolite aflatoxin B1 (AFB1), serious endangers human health. We previous revealed that histone methyltransferase complex COMPASS plays a crucial role in regulating various biological processes of A. flavus, but underlying mechanism is unclear...
ORGANISM(S): Aspergillus flavus 
2026-02-02 | GSE285953 | GEO
GenomicsThe COMPASS subunit Bre2 targets CRF Arp9 to regulate the bio-synthesis of secondary metabolite AFB1 and virulence in Aspergillus flavus [ATAC-seq]
The COMPASS subunit Bre2 targets CRF Arp9 to regulate the bio-synthesis of secondary metabolite AFB1 and virulence in Aspergillus flavus [ATAC-seq]
PRJNA1207040 | ENA
UnknownComparison of brexpiprazole, aripiprazole, and placebo for Japanese major depressive disorder: A systematic review and network meta-analysis.
Not available
S-EPMC10932760 | biostudies-literature
UnknownCrystal Structure of the COMPASS H3K4 Methyltransferase Catalytic Module.
Not available
S-EPMC6108940 | biostudies-literature
UnknownChromatin-level regulation of biosynthetic gene clusters.
Not available
S-EPMC2891026 | biostudies-literature
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