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Aspergillus flavus, along with its notorious secondary metabolite aflatoxin B1 (AFB1), serious endangers human health. We previous revealed that histone methyltransferase complex COMPASS plays a crucial role in regulating various biological processes of A. flavus, but underlying mechanism is unclear...
ORGANISM(S): Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / NRRL 3357 / JCM 12722 / SRRC 167) 
2026-02-08 | PXD060646 | Pride
The chromatin remodeling factor Arp9 modulates the drug-resistance of Aspergillus flavus
Aspergillus flavus, along with its notorious secondary metabolite aflatoxin B1 (AFB1), serious endangers human health. We previous revealed that histone methyltransferase complex COMPASS plays a crucial role in regulating various biological processes of A. flavus, but underlying mechanism is unclear...
ORGANISM(S): Aspergillus flavus 
2026-02-02 | GSE285953 | GEO
The COMPASS subunit Bre2 targets CRF Arp9 to regulate the bio-synthesis of secondary metabolite AFB1 and virulence in Aspergillus flavus [ATAC-seq]
Transcriptome analysis, combined with RT-qPCR validation and high-performance liquid chromatography (HPLC) assay, determined that the absence of Arp9 down-regulated the expression levels of genes Erg3 and Erg6 in the ergosterol synthesis pathway, resulted in reducing the amount of ergosterol synthes...
ORGANISM(S): Aspergillus flavus 
2026-02-12 | GSE279121 | GEO
The COMPASS subunit Bre2 targets CRF Arp9 to regulate the bio-synthesis of secondary metabolite AFB1 and virulence in Aspergillus flavus
In this study, To determine the chromatin distribution pattern of Bre2-regulated H3K4me3 at the genome-wide level, we used the BRE2 knockout strain constructed in this study as a control; Chip-sequencing (ChIP-seq) experiments were performed in WT strains using an antibody to H3K4me3 to search for t...
ORGANISM(S): Aspergillus flavus 
2026-02-02 | GSE285749 | GEO
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