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TranscriptomicsExpression data from RCAS PDGFB/Nestin tv-A glioma cells within Ptprd+/+p16-/- (n=2), Ptprd+/-p16-/- (n=2), and Ptrpd-/-p16-/- (n=3) mice.
PTPRD is a tumor suppressor of glioma that is frequently co-deleted with CDKN2A/p16. We show that Ptprd and p16 cooperate to promote gliomagenesis in the RCAS PDGFB / Nestin tv-A glioma mouse model. We found unique gene expression changes within tumor cells of Ptprd+/-p16-/- vs. Ptprd+/+p16-/- and P...
ORGANISM(S): Mus musculus 
2014-06-02 | E-GEOD-55061 | biostudies-arrayexpress
MetabolomicsA red wine intervention does not modify plasma trimethylamine N-oxide but is associated with broad shifts in the plasma metabolome and gut microbiota composition

BACKGROUND: Gut microbiota profiles are closely related to cardiovascular diseases through mechanisms that include the reported deleterious effects of metabolites, such as trimethylamine N-oxide (TMAO), which have been studied as diagnostic and therapeutic targets. Moderate red ...

2024-05-09 | MTBLS310 | MetaboLights
UnknownYouth Functioning and Organizational Success for West African Regional Development (Youth FORWARD): Study Protocol.
Not available
S-EPMC11870143 | biostudies-literature
UnknownN-cadherin haploinsufficiency increases survival in a mouse model of pancreatic cancer.
Not available
S-EPMC3714178 | biostudies-literature
UnknownEstimating the effect of timetabling decisions on the spread of SARS-CoV-2 in medium-to-large engineering schools in Canada: an agent-based modelling study.
Not available
S-EPMC8695572 | biostudies-literature
UnknownN-acetylcysteine prevents loss of dopaminergic neurons in the EAAC1-/- mouse.
Not available
S-EPMC4096233 | biostudies-literature
TranscriptomicsWNT Pathway Signalling in Kidney Transplants with Microvascular Injury
Kidney transplant recipients with biopsy-proven microvascular injury (MVI) have increased risk for allograft failure. MVI is often caused by antibody-mediated injury that is resistant to available treatments. Current diagnostic methods are also inadequate, with interobserver variability in tradition...
ORGANISM(S): Homo sapiens 
2019-06-15 | E-GEOD-115989 | biostudies-arrayexpress
ProteomicsFERM domain protein 3 Kidney Biopsy
We examined the transcriptional profile of human kidney biopsies, aiming to provide insight into the mechanisms of progressive CKD. This approach led to the identification of FERM domain protein 3, (FRMD3) as a molecular driver of disease. Transcriptome profiling was performed in human renal biopsy ...
ORGANISM(S): Homo sapiens (Human) 
2024-11-06 | PXD015297 | Pride
Kidney human ferm domain protein 3 
UnknownRegorafenib plus Vincristine and Irinotecan in Pediatric Patients with Recurrent/Refractory Solid Tumors: An Innovative Therapy for Children with Cancer Study.
Not available
S-EPMC10618645 | biostudies-literature
TranscriptomicsTranscription profiling by array of brain from zebrafish treated with ethanol or nicotine suggests conservation of neuro-adaptation pathways
Effect of ethanol or nicotine exposure on gene expression compared to control. Duplicate arrays from ethanol or nicotine treated animals compared with triplicate arrays from paired control animals. In total 4 treatment arrays (2 ethanol, 2 nicotine) and 3 control arrays (from control animals treate...
ORGANISM(S): Danio rerio 
2008-05-01 | E-MEXP-1301 | biostudies-arrayexpress
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