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TranscriptomicsSuccessful and failed human liver regeneration are characterized by the coordinated expression of distinct microRNAs
The liverM-bM-^@M-^Ys remarkable capacity to regenerate allows it to carry out vital life-supporting functions despite unrelenting pathogen and toxin-induced injury. Unchecked, this capability also leads to cirrhosis, a burgeoning global disease burden. Existing animal models only partially recapitu...
ORGANISM(S): Homo sapiens 
2013-05-06 | E-GEOD-36146 | biostudies-arrayexpress
TranscriptomicsDistinct Micro-RNA profiles are associated with severity of hepatitis C virus recurrence and acute cellular rejection after liver transplant
Recurrent hepatitis C virus (rHCV) is universal post-liver transplantation (LT), with accelerated fibrosis rates compared to non-transplanted patients. rHCV is associated with increased mortality and morbidity post-transplant and is a leading indication for re-transplantation. We hypothesized that m...
ORGANISM(S): Homo sapiens 
2013-09-17 | E-GEOD-40113 | biostudies-arrayexpress
TranscriptomicsGene expression microarray analysis of early oxygen-induced retinopathy (OIR)
Different inbred strains of rats differ in their susceptibility to OIR, an animal model of human retinopathy of prematurity. We examined gene expression profiles in Fischer 344 (F344, resistant to OIR) and Sprague Dawley (SD, susceptible to OIR) rats at the early time point of day 3 to identifying g...
ORGANISM(S): Rattus norvegicus 
2009-11-12 | E-GEOD-18998 | biostudies-arrayexpress
TranscriptomicsUse of microarray analyses to determine the effect of hyperoxia and hypoxia on gene expression in early oxygen-induced retinopathy (OIR).
Different inbred strains of rats differ in their susceptibility to OIR, an animal model of human retinopathy of prematurity. We examined gene expression profiles in Fischer 344 (F344, resistant to OIR) and Sprague Dawley (SD, susceptible to OIR) rats at the early time points of day 5 (in response to...
ORGANISM(S): Rattus norvegicus 
2012-02-24 | E-GEOD-36037 | biostudies-arrayexpress
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