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ProteomicsIntramolecular disulfide bridges in Voltage-Dependent Anion Channel 2 (VDAC2) protein from Rattus norvegicus revealed by high resolution mass spectrometry.
Voltage-Dependent Anion Channel isoforms (VDAC1, VDAC2, VDAC3) are relevant component of the outer mitochondrial membrane and play crucial role in cellular processes, in regulation of metabolism and in survival pathways. Recently, we reported the characterization of the oxidation pattern of cysteine...
ORGANISM(S): Rattus rattus (Black rat) 
2024-06-16 | PXD044041 | Pride
High-resolution mass spectrometry  intramolecular disulfide bridges  rattus voltage-dependent anion selective channel isoform 2 (rvdac2)  cysteine redox state  structural characterization. 
ProteomicsDetermination of disulfide bridges of human PGAP4 protein
To determine disulfide bonds of human PGAP4 protein
ORGANISM(S): Homo sapiens (Human) 
2018-01-30 | PXD008137 | Pride
Lc-msms Disulfide bridges Pgap4 
UnknownClosing the gap towards super-long suspension bridges using computational morphogenesis.
Not available
S-EPMC7264174 | biostudies-literature
UnknownSister chromatids separate during anaphase in a three-stage program as directed by interaxis bridges.
Not available
S-EPMC8915976 | biostudies-literature
ProteomicsMechanistic basis for the spatiotemporal assembly of the Bloom Syndrome complex on ultrafine DNA bridges
The BTRR (BLM/TOP3A/RMI1/RMI2) complex resolves DNA replication and recombination intermediates, as well as mitotic DNA intertwinements, yet how its diverse activities are regulated remains unclear. Here, we identify key determinants of stable assembly of the BTRR complex on ultrafine DNA bridges (U...
ORGANISM(S): Homo sapiens (Human) 
2026-07-30 | PXD081930 | Pride
Bloom syndrome complex Ultrafine dna bridges 
MetabolomicsExometabolomic-enabled discovery of compounds associated with Escherichia coli O157:H7 population dynamics in the lettuce phyllosphere

Contamination of fresh produce with human pathogens remains a serious public health and economic concerns due to the absence of effective kill steps in the farm-to-fork chain. In particular, the pathogenic Escherichia coli O157:H7 has been implicated in multiple illness outbreaks linked to lettuc...

2026-06-11 | MTBLS14653 | MetaboLights
TranscriptomicsSmall RNA accumulation in Transposable Element-silent and Transposable Element-active epigenomes
Background: The small RNAs that Transposable Elements generate are vastly different when they are transcriptionally silenced compared to when they are transcriptionally activated. We performed the deep sequencing of small RNAs in a number of small RNA biogenesis mutants in both Transposable Element-...
ORGANISM(S): Arabidopsis thaliana 
2014-11-14 | E-GEOD-57191 | biostudies-arrayexpress
UnknownStructure-function analysis of Avian β-defensin-6 and β-defensin-12: role of charge and disulfide bridges.
Not available
S-EPMC5016922 | biostudies-literature
GenomicsThe SPOC domain is a phosphoserine binding module that bridges transcription machinery with co- and post-transcriptional regulators - ChIP-seq
The heptarepeats of the C-terminal domain of Pol II are extensively modified throughout the transcription cycle. The CTD coordinates RNA synthesis and processing by recruiting transcription regulation factors as well as RNA capping, splicing and 3’end processing factors. The SPOC domain of PHF3 was ...
ORGANISM(S): Homo sapiens 
2023-02-22 | E-MTAB-11506 | biostudies-arrayexpress
ProteomicsAdaptation of CysPAT technique to characterize endogenous S-nitrosylation in RAW264.7 cells
The aim of the study was to adapt the CysPAT technique to efficiently identify and characterize endogenous S-nitrosylation in cells under physiological conditions of an experiment from a small amount of sample. Using a macrophage cell line RAW 264.7 we compared the efficacy of the method in the iden...
ORGANISM(S): Mus musculus (Mouse) 
2022-02-22 | PXD008182 | Pride
Post-translational modifications (ptms) Immune system S-nitrosylation Proteomics Macrophages 
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