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TranscriptomicsEstrogen Coordinates Translation and Transcription Revealing a Role for NRSF in Human Breast Cancer Cells
Analysis of estrogen receptor (ER)-positive MCF7 cell total RNA expression and polysome-assiciated RNA expression following treatment with estradiol (E2) and vehicle (etoh). We used expression microarrays to measure polysome association and total RNA abundance in E2 treated MCF7. These data, along ...
ORGANISM(S): Homo sapiens 
2010-05-07 | E-GEOD-18592 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation profiling of human HeLa cells after immunoprecipitation of ptb65 associated mRNAs
PTB is multifunctional RNA binding protein reported to be involved in splicing, 3' -end processing, stability and translational regulation. Sample preparation methods (Gama-Carvalho et al, 2006, submitted); Suspension HeLa cells were grown in DMEM, 10% FCS, Pen/Strep and split 1:2 the day before har...
ORGANISM(S): Homo sapiens 
2008-06-14 | E-GEOD-6021 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation of HeLa cells after immunoprecipitation of U2AF65 associated mRNAs
U2AF65 is an essential splicing factor involved in the 3'splice site recognition dureing the first steps of spliceosome assembly. In addition, this protein has nucleocytoplasmic shuttling activity and the Drosophila homologue has been implicated in mRNA export. We have used microarray hybridization ...
ORGANISM(S): Homo sapiens 
2008-06-14 | E-GEOD-6022 | biostudies-arrayexpress
TranscriptomicsmiRNA Profiling in mucosal biopsies of Eosinophilic Esophagitis patients pre and post glucocorticoid steroid treatment
Eosinophlic esophagitis (EoE) is increasely recognized as an antigen-drived disorder. The goal of this study is to reveal the miRNA expression changes in EoE before and after a successful glucocorticoid steroid treatment. Total RNA was extracted from the esophageal epithelial layers of 5 paired para...
ORGANISM(S): Homo sapiens 
2012-03-23 | E-GEOD-36726 | biostudies-arrayexpress
TranscriptomicsMicroRNA Profiling in Mucosal Biopsies of Eosinophilic Esophagitis Patients Pre and Post Glucocorticoid Steroid Treatment and Relationship with mRNA Target Expression
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2012-03-23 | E-GEOD-36727 | biostudies-arrayexpress
UnknownDorsal Amygdala Neurotrophin-3 Decreases Anxious Temperament in Primates.
Not available
S-EPMC6999854 | biostudies-literature
UnknownIntegrating Machine Learning With Microsimulation to Classify Hypothetical, Novel Patients for Predicting Pregabalin Treatment Response Based on Observational and Randomized Data in Patients With Painful Diabetic Peripheral Neuropathy.
Not available
S-EPMC6827520 | biostudies-literature
UnknownUsing time series analysis approaches for improved prediction of pain outcomes in subgroups of patients with painful diabetic peripheral neuropathy.
Not available
S-EPMC6283469 | biostudies-literature
UnknownComplement activity and complement regulatory gene mutations are associated with thrombosis in APS and CAPS.
Not available
S-EPMC6978159 | biostudies-literature
TranscriptomicsTranscription profiling by array of human MCF cells treated with estrogen
The estrogen receptor is the master transcriptional regulator of breast cancer phenotype and the archetype of a molecular therapeutic target. We mapped all estrogen receptor and RNA polymerase II binding sites on a genome-wide scale, identifying the authentic cis binding sites and target genes, in b...
ORGANISM(S): Homo sapiens 
2008-06-11 | E-GEOD-11324 | biostudies-arrayexpress
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