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Deletion of transcription factors DevR and AcdX in Aspergillus fumigatus causes increased/decreased susceptibility to the antifungal Olorofim. In order to characterise the basis of differential Olorofim susceptibility, and distinguish which metabolic pathways these transcription factors regulate, RN...
ORGANISM(S): Aspergillus fumigatus 
Whole genome sequencing of SYBARIS Aspergillus spp. known to be multi-drug resistant and difficult to treat. Aim of this experiment is to investigate the genetic basis of susceptibility to disease and elucidate molecular mechanisms of drug resistance in these strains.
ORGANISM(S): Aspergillus nidulans 
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