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The analysis of bronchoalveolar lavage fluid (BALF) using mass spectrometry-based metabolomics can provide insight into lung diseases, such as asthma. However, the important step of compound identification is hindered by the lack of a small molecule database that is specific for BALF. Here we descri...
2018-02-09 | MTBLS591 | MetaboLights
In dogs, a species for which markers of cell populations are often limiting, we sought to evaluate in an unbiased way the heterogeneity of cell subpopulations in the bronchoalveolar lavage fluid of healthy dogs, by single-cell RNA-sequencing.
ORGANISM(S): Canis lupus familiaris 
Bronchoalveolar lavage samples collected from lung transplant recipients. Numeric portion of sample name is an arbitrary patient ID and AxBx number indicates the perivascular (A) and bronchiolar (B) scores from biopsies collected on the same day as the BAL fluid was collected. Several patients hav...
ORGANISM(S): Homo sapiens 
The scope of this project is to investigate dynamic and persistent proteomic changes in tuberculosis (TB) patients during the course of treatment by analyzing paired bronchial alveolar lavage fluid (BALf) and serum samples collected at diagnosis and after 25 weeks of therapy. By comparing patient sa...
ORGANISM(S): Mycobacterium tuberculosis H37Rv Homo sapiens (Human) 
2026-03-17 | PXD073337 | Pride
Rationale: Lipopolysaccharide (LPS) is ubiquitous in the environment. Inhalation of LPS has been implicated in the pathogenesis and/or severity of several lung diseases, including pneumonia, chronic obstructive pulmonary disease and asthma. Alveolar macrophages are the main resident leukocytes expos...
ORGANISM(S): Homo sapiens 
Clinical subphenotypes of asthma are characterized by pathological, cellular, and molecular heterogeneity of the airway. Gene expression profiling of airway inflammatory cells in diseased patients by microarray analysis will provide insight into the molecular heterogeneity and support the developmen...
ORGANISM(S): Homo sapiens 
Acute respiratory distress syndrome (ARDS) is a severe and complex critical illness, characterized by its heterogeneous clinical presentation, making accurate clinical definition and effective treatment challenging. We hypothesized that advanced molecular analyses of matched plasma and bronchial alv...
ORGANISM(S): Homo sapiens (Human) 
2026-02-16 | PXD060437 | Pride
To capture interplay between biological pathways we analyzed the proteome from matched lung tissue and bronchoalveolar lavage fluid (BALF) of individual allergen-naive and house dust mite (HDM)-challenged BALB/c mice, a model of allergic asthma. Unbiased label-free LC-MS/MS analysis quantified 2,675...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2020-08-24 | MSV000086003 | MassIVE
We used the scRNA-seq to characterize disease-related heterogeneity within cell populations of macrophages/monocytes in the bronchoalveolar lavage fluid from West Highland white terriers either healthy or affected with canine idioapthic pulmonary fibrosis. The disease is still not well understood, o...
ORGANISM(S): Canis lupus familiaris 
In this study broncho-alveolar lavage fluid (BALF) from mice infected with influenza A virus, PR8 (280 PFU) was analyzed for lipidomic host response in comparison with the mock infected animals. Time Points: 6, 9, 11, 13 and 19 days post infection, done in 8-10 replicates.)
2013-05-30 | MTBLS32 | MetaboLights
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