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MetabolomicsGut Microbiota and Metabolomic Changes Across Preterm Stages: Potential Associations with Bronchopulmonary Dysplasia

The coordinated postnatal development of the gut microbiome and metabolome is essential for preterm infant health, yet its disruption is increasingly linked to adverse outcomes such as bronchopulmonary dysplasia (BPD). In this study, we performed an integrated multi-omics analysis of fecal sample...

2026-02-05 | MTBLS13364 | MetaboLights
TranscriptomicsA genomewide association study for bronchopulmonary dysplasia using DNA pooling
Bronchopulmonary dysplasia (BPD) is the most common chronic respiratory disease in premature infants. Recent studies have highlighted the contribution of genetic factors to BPD susceptibility. Our aim was to identify the genetic variants associated to BPD, through a genomewide association study. Two...
ORGANISM(S): Homo sapiens 
2011-11-22 | E-GEOD-22284 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human low gestational age newborns as predictors of bronchopleural pulmonary dysplasia
One third to one half of all infants born before the 28th wek of gestation develop BPD bronchopulmonary dysplasia. Our objective is to evaluate the feasibility of using expression profiling in umbilical cord tissue to discover molecular signatures for developmental staging and for risk of BPD. Expe...
ORGANISM(S): Homo sapiens 
2008-06-16 | E-GEOD-8586 | biostudies-arrayexpress
GenomicsMicrobiome features of bronchopulmonary dysplasia
Microbiome features of bronchopulmonary dysplasia
PRJNA1105631 | ENA
UnknownMagentic Resonance Imaging Evaluation of Regional Lung Vts in Severe Neonatal Bronchopulmonary Dysplasia.
Not available
S-EPMC7528778 | biostudies-literature
TranscriptomicsRNA-seq of peripheral whole blood from ten healthy preterm infants and ten preterm infants with bronchopulmonary dysplasia
We procured peripheral whole blood from ten healthy preterm infants and ten preterm infants with bronchopulmonary dysplasia
ORGANISM(S): Homo sapiens 
2024-10-27 | E-MTAB-14506 | biostudies-arrayexpress
TranscriptomicsmRNA expression profile in a murine model of hyperoxia-induced bronchopulmonary dysplasia
We performed miRNA and mRNA profiling at postnatal day 14 and day 29 to compare hyperoxia-induced bronchopulmonary dysplasia and wild type. We built potential miRNA-mRNA interaction networks specific to brochopulmonary dysplasia. Replicated time course of mouse lung development at 2 time points (P1...
ORGANISM(S): Mus musculus 
2012-04-30 | E-GEOD-25286 | biostudies-arrayexpress
ProteomicsSIRT3 Deficiency Drives Alveolar Epithelial Mitochondrial Dysfunction in Hyperoxia-Induced Bronchopulmonary Dysplasia via PDHA1 Hyperacetylation
Neonates were pooled and randomized at P0 to circumvent litter bias and subjected to either normoxia or hyperoxia (85% O2) for 14 days.
ORGANISM(S): Mus musculus (Mouse) 
2026-06-02 | PXD078668 | Pride
Bronchopulmonary dysplasia  pdha1  sirt3  hyperacetylation 
ProteomicsPlasma Extracellular Vesicles from Bronchopulmonary Dysplasia Infants Initiate Inflammation and Abnormal Angiogenesis in Neonatal Murine Retinas
To investigate the mechanisms of plasma extracellular vesicles from preterm infants with bronchopulmonary dysplasia (BPD) elicit inflammation and abnormal angiogenesis in neonatal wild-type mouse retinas.
ORGANISM(S): Homo sapiens (Human) 
2026-03-02 | PXD068467 | Pride
Neovascularization Extracellular vesicles Bpd Rop Retinal inflammation 
TranscriptomicsmicroRNA expression profile in a murine model of hyperoxia-induced bronchopulmonary dysplasia
We performed miRNA and mRNA profiling at postnatal day 14 and day 29 to compare hyperoxia-induced bronchopulmonary dysplasia and wild type. We built potential miRNA-mRNA interaction networks specific to brochopulmonary dysplasia. Replicated time course of mouse lung development at 2 time points (P14...
ORGANISM(S): Mus musculus 
2012-05-01 | E-GEOD-25290 | biostudies-arrayexpress
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