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MetabolomicsHuman Gut Microbiota from Autism Spectrum Disorder Promote Behavioral Symptoms in Mice
Autism spectrum disorder (ASD) manifests as alterations in complex human behaviors including social communication and stereotypies. In addition to genetic risks, the gut microbiome differs between typically-developing (TD) and ASD individuals, though it remains unclear whether the microbiome contrib...
2019-07-04 | MTBLS726 | MetaboLights
UnknownTumour cell invasiveness and response to chemotherapeutics in adipocyte invested 3D engineered anisotropic collagen scaffolds.
Not available
S-EPMC6107500 | biostudies-literature
MetabolomicsLipid biomarkers for algal resistance to viral infection in the ocean

Marine viruses play a key role in regulating phytoplankton populations, greatly affecting the biogeochemical cycling of major nutrients in the ocean. Resistance to viral infection has been reported for various phytoplankton species under laboratory conditions. Nevertheless, the occurrence of resi...

2023-06-12 | MTBLS3323 | MetaboLights
MetabolomicsDirect on-swab metabolic profiling of vaginal microbiome:host interactions during pregnancy and preterm birth

The pregnancy vaginal microbiome contributes to risk of preterm birth, the primary cause of death in children under 5 years of age. Here we describe direct on-swab metabolic profiling by Desorption Electrospray Ionization Mass Spectrometry (DESI-MS) for sample preparation-free characterisation of...

2021-09-23 | MTBLS717 | MetaboLights
TranscriptomicsPancreatic Cancer 1
This is the experiment set used for a paper written in collaboration with Hopkins. It compares genes that are differentially expressed between normal pancreas, pancreatic cell lines and pancreatic adenocarcinoma. Pancreatic cancer is the fifth leading cause of cancer death in the United States. We u...
ORGANISM(S): Homo sapiens 
2005-11-23 | E-GEOD-3654 | biostudies-arrayexpress
MetabolomicsInfluence of early life exposure, host genetics and diet on the mouse gut microbiome and metabolome
Although the gut microbiome plays important roles in host physiology, health and disease, we lack understanding of the complex interplay between host genetics and early life environment on the microbial and metabolic composition of the gut. We used the genetically diverse Collaborative Cross mouse s...
2016-10-05 | MTBLS345 | MetaboLights
UnknownAdjuvant-dependent innate and adaptive immune signatures of risk of SIVmac251 acquisition.
Not available
S-EPMC5916782 | biostudies-literature
TranscriptomicsTranscriptomic profiling of rhesus macaques vaccinated with ALVAC-SIV/gp120 adjuvanted in Alum or MF59.
The Canarypox/gp120/Alum vaccines decreased the risk of HIV acquisition in humans. We demonstrate here the efficacy of this vaccine regimen also in the SIVmac251 macaque model when we used the alum but not the MF59 adjuvant. Analysis of innate and adaptive cell responses, envelope antibodies Fc prof...
ORGANISM(S): Macaca mulatta 
2016-05-29 | E-GEOD-72624 | biostudies-arrayexpress
ProteomicsProteomic analysis of Bombus terrestris queen haemolymph
Enabled by recently available genomic resources for bumblebees, nano LC-MS/MS based proteomics was conducted to characterise the queen haemolymph proteome. The resulting mass spectrometry data were also utilised in a proteogenomic capacity to identify proteins missing from official gene sets and to ...
ORGANISM(S): Bombus terrestris (Buff-tailed bumblebee) (Apis terrestris) 
2015-02-24 | PXD001644 | Pride
Bumblebee Proteogenomics Haemolymph profile Queen 
ProteomicsBumblebee venom - The genomes of two key bumblebee species with primitive eusocial organization
This experiment provide a comprehensive overview of proteins present in bumblebee venom.
ORGANISM(S): Bombus terrestris (Buff-tailed bumblebee) (Apis terrestris) 
2015-04-29 | PXD001623 | Pride
Venom Toxing Bumblebee 
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