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MetabolomicsA metabolomic study of adipose tissue in mice with a disruption of the circadian system

Adipose tissue functions in terms of energy homeostasis as a rheostat for blood triglyceride, regulating its concentration, in response to external stimuli. In addition it acts as a barometer to inform the central nervous system of energy levels which can vary dramatically between meals and accor...

2017-10-27 | MTBLS390 | MetaboLights
TranscriptomicsColonization, luminescence, and autoinducer effects on host transcription during development of squid-vibrio association
The light-organ symbiosis between the squid Euprymna scolopes and the luminous bacterium Vibrio fischeri offers the opportunity to decipher the hour-by-hour events that occur during the natural colonization of an animal's epithelial surface by its microbial partners. To determine the genetic basis o...
ORGANISM(S): Euprymna scolopes 
2008-11-10 | E-GEOD-13533 | biostudies-arrayexpress
TranscriptomicsHypoxia response in C. neoformans in H99, CM092 and CM098
(1) The identification of genes that are transcriptionally regulated in response to exposure to hypoxia (~0.2% oxygen) in H99 (WT) and strains CM092 and CM098. (2) The identification of genes that are differentially-regulated in the strain CM093 compared to H99 (WT) Keywords: hypoxia response, compa...
ORGANISM(S): Filobasidiella neoformans 
2010-06-12 | E-GEOD-6226 | biostudies-arrayexpress
UnknownCell line and patient-derived xenograft models reveal elevated CDCP1 as a target in high-grade serous ovarian cancer.
Not available
S-EPMC4815773 | biostudies-literature
UnknownHealth Departments With A Commitment To Health Equity: A More Skilled Workforce And Higher-Quality Collaborations.
Not available
S-EPMC5975259 | biostudies-literature
TranscriptomicsOverexpression of the transcription factor GAT201 in Cryptococcus neoformans var. grubii (serotype A, H99)
Comparison of transcriptional profiles of WT Cryptococcus neoformans (H99) and strain CM126 (pRPL2b-GAT201) which overexpresses the transcription factor GAT201 using a ribosomal protein promoter Keywords: Genetic modification WT vs. CM126 competitive hybridization. 4 biological replicates including...
ORGANISM(S): Filobasidiella neoformans 
2010-05-26 | E-GEOD-10750 | biostudies-arrayexpress
UnknownOvarian carcinoma subtypes are different diseases: implications for biomarker studies.
Not available
S-EPMC2592352 | biostudies-literature
ProteomicsDiscovery and characterization of a chemical probe targeting the zinc-finger ubiquitin-binding domain of HDAC6
Cellular selectivity of a chemical probe for the UBD of HDAC6. A biotinylated analog of HDAC6 chemical probe SGC-UBD253 bound to streptavidin beads was used to enrich HDAC6 from cytoplasmic fraction of HEK293 lysate. A triplicate of each condition - competition with probe, control, DMSO - was done.
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD039880 | Pride
Ubiquitin binding domain Chemical probe Ubd Chemoproteomics Hdac6 
UnknownKisspeptin and GPR54 immunoreactivity in a cohort of 518 patients defines favourable prognosis and clear cell subtype in ovarian carcinoma.
Not available
S-EPMC2200658 | biostudies-literature
TranscriptomicsTGF-beta-mediated microRNA expression in breast cancer cells
We utilized 3D-organotypic cultures whose physical properties were altered by inclusiong of type I collagen to create biomechanically rigid microenvironments that approximated those typically observed in primary mammary tumors. Compliant 3D-organotypic cultures were also generated to recapitulate t...
ORGANISM(S): Mus musculus 
2012-10-31 | E-GEOD-41274 | biostudies-arrayexpress
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