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TranscriptomicsRegulation of Fetal Liver Growth in a Model of Diet Restriction in the Pregnant Rat
The present study was designed to test the hypothesis that limited growth of the fetal liver in the model of maternal fasting is independent of well-characterized signaling mechanisms that are known to regulate somatic growth in adult animals. We profiled the fetal hepatic transcriptome and translat...
ORGANISM(S): Rattus norvegicus 
2016-07-18 | E-GEOD-77112 | biostudies-arrayexpress
TranscriptomicsDifferential gene expression from microarray analysis distinguishes woven and lamellar bone formation in the rat ulna following mechanical loading
The objective of our study was to use a microarray to distinguish the molecular responses between woven and lamellar bone formation induced through mechanical loading. The micorarray identified numerous genes and pathways that were differentially regulated for woven, but not lamellar bone formati...
ORGANISM(S): Rattus norvegicus 
2013-01-01 | E-GEOD-27065 | biostudies-arrayexpress
ProteomicsThe Staphylococcus aureus Host Cell Genetic Adhesion Network
Adhesion of Staphylococcus aureus to the host’s skin and mucosae enables asymptomatic colonization and the establishment of infections. This process is facilitated by cell wall-anchored (CWA) adhesins that are covalently attached to the bacterial cell wall and exhibit affinity for host ligands. To g...
ORGANISM(S): Staphylococcus aureus 
2023-03-04 | PXD018514 | Pride
Anti-adhesives  anti-virulence  staphylococcus aureus  mrsa  antibiotic resistance  cell wall-anchored proteins  autolysin  adhesome 
TranscriptomicsSexual Dimorphic Regulation of Liver Gene Expression by Glucocorticoids
Males and females exhibit differences in the incidence of many major diseases including auto-immune diseases, hepatocellular carcinoma, diabetes, and osteoporosis, which all have important inflammatory components in their etiology. Glucocorticoids are the primary physiological anti-inflammatory horm...
ORGANISM(S): Rattus norvegicus 
2010-10-01 | E-GEOD-13461 | biostudies-arrayexpress
TranscriptomicsGene expression comparison of E14.5 Foxd1 null and wild type kidneys
Forkhead transcription factors are essential for diverse processes in early embryonic development and organogenesis. Foxd1 is required during kidney development and its inactivation results in failure of nephron progenitor cell differentiation. Foxd1 is expressed in interstitial cells adjacent to ne...
ORGANISM(S): Mus musculus 
2013-11-14 | E-GEOD-52354 | biostudies-arrayexpress
TranscriptomicsHIF-2alpha Knockdown in A498 (VHL-/-) ccRCC cells
HIF-2alpha is essential for (VHL-/-) ccRCC subcutaneous tumor growth in mice, and in tumor cell lines, its inhibition results in increased ROS accumulation, tumor cell death and responsiveness to radiation treatment. We have utilized transcriptional profiling to screen for putative HIF-2alpha target...
ORGANISM(S): Homo sapiens 
2009-08-27 | E-GEOD-16622 | biostudies-arrayexpress
TranscriptomicsTunable protein synthesis by transcript isoforms in human cells (Transcript Isoforms in Polysomes sequencing: TrIP-seq)
Eukaryotic genes generate multiple mRNA transcript isoforms though alternative transcription, splicing, and polyadenylation. However, the relationship between human transcript diversity and protein production is complex as each isoform can be translated differently. We fractionated a polysome profil...
ORGANISM(S): Homo sapiens 
2016-01-11 | E-GEOD-69352 | biostudies-arrayexpress
UnknownThe bii4africa dataset of faunal and floral population intactness estimates across Africa's major land uses.
Not available
S-EPMC10861571 | biostudies-literature
TranscriptomicsRapamycin effect on gene expression: dependence on c-Myc
This experiment utilized rat fibroblasts that are wild-type for c-Myc (TGR-1 cells) and null for c-Myc (HO15.19 cells). Both were treated treated with rapamycin for 24 hr (comparison group, vehicle control). Cells were studied under conditions that supported proliferation. Rapamycin (50nM or DMSO ...
ORGANISM(S): Rattus norvegicus 
2010-10-25 | E-GEOD-18845 | biostudies-arrayexpress
GenomicsABO_OICR_DATASET - samples
OICR PANCREATIC CANCER DATASET
EGAD00001000262 | EGA
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