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GenomicsEpigenome in brown and white adipose tissue
For comparative epigenomic analysis of brown fat and white fat in mice, H3K27ac and PolII ChIP-seq were performed in each depot. H3K27ac histone modification and PolII transcription profiles in mouse brown and white adipose tissues
ORGANISM(S): Mus musculus 
2015-02-10 | E-GEOD-63964 | biostudies-arrayexpress
GenomicsCistromic and epigenomic changes in Prdm16 knock-out brown adipose tissue
Prdm16 is a transcription factor that drives a complete program of brown adipocyte differentiation, but the mechanism by which Prdm16 activates gene transcription remains unknown. Utilizing ChIP-seq teqhnique, we found that Prdm16 binds to chromatin at/near many brown fat-selective genes in BAT. Int...
ORGANISM(S): Mus musculus 
2015-02-10 | E-GEOD-63965 | biostudies-arrayexpress
UnknownCost-effectiveness of Crohn's disease post-operative care.
Not available
S-EPMC4814750 | biostudies-literature
TranscriptomicsComparison of Saffron and Photobiomodulation on the light damaged rat retina.
Aim: To identify the genes and non-coding RNAs (ncRNAs) involved in the neuroprotective actions of a dietary anti-oxidant (saffron) and of photobiomodulation. Methods: We used a previously published assay of photoreceptor damage, in which albino Sprague Dawley rats raised in dim cyclic illumination ...
ORGANISM(S): Rattus norvegicus 
2010-07-16 | E-GEOD-22818 | biostudies-arrayexpress
ProteomicsMitochondrial reprogramming underlies resistance to BCL-2 inhibition in lymphoid malignancies
Guieze R, Liu VM, Rosebrock D, Jourdain AA, Hernandez-Sanchez M, Martinez A, Sun J, Baranowski K, Thompson PA, Heo J, Cartun Z, Aygun O, Notarangelo G, Livitz D, Li S, Hacken ET, Davids MS, Iorgelescu JB, Zhang W, Biran A, Fernandes SM, Brown JR, Ana Lako A, Ciantra ZB, Keskin DB, Udeshi ND, Wierd...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-03-02 | MSV000083512 | MassIVE
UnknownA DEL-1/αvβ3 integrin axis promotes brown adipocyte progenitor proliferation and cold-induced brown adipose tissue adaptation.
Not available
S-EPMC12391742 | biostudies-literature
TranscriptomicsAmino acid deprivation due to overexpression of UCP1 in skeletal muscle: signalling via FGF-21
Recent studies on mouse and human skeletal muscle (SM) demonstrated the important link between mitochondrial function and the cellular metabolic adaptation. To identify key compensatory molecular mechanisms in response to chronic mitochondrial distress, we analyzed mice with ectopic SM respiratory u...
ORGANISM(S): Mus musculus 
2015-02-17 | E-GEOD-45991 | biostudies-arrayexpress
UnknownMaternal versus environmental contributions to the piglet pioneer microbiome.
Not available
S-EPMC11301562 | biostudies-literature
UnknownRandomised clinical trial of a 16 mg vs 24 mg maintenance daily dose of buprenorphine to increase retention in treatment among people with an opioid use disorder in Rhode Island: study protocol paper.
Not available
S-EPMC11551980 | biostudies-literature
UnknownActivation of the ubiquitin proteasome pathway in a mouse model of inflammatory myopathy: a potential therapeutic target.
Not available
S-EPMC4080828 | biostudies-literature
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