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MetabolomicsAbsence of MCJ/DnaJC15 promotes brown adipose tissue thermogenesis
Obesity poses a global health challenge, demanding a deeper understanding of adipose tissue (AT) and its mitochondria. This study describes the role of the mitochondrial protein Methylation-controlled J protein (MCJ/DnaJC15) in orchestrating brown adipose tissue (BAT) thermogenesis. Here we show how...
2024-10-31 | MTBLS11505 | MetaboLights
TranscriptomicsExpression data from the seed coats of black (iRT) and brown (irT) soybean variant for alleles of the R locus
The seed coat of black (iRT) soybean with the dominant R allele begins to accumulate cyanic pigments at the transition stage of seed development (300 – 400 mg fresh seed weight), whereas the brown (irT) nearly-isogenic seed coat with the recessive r allele lacks cyanic pigments at all stages of seed...
ORGANISM(S): Glycine max 
2011-08-22 | E-GEOD-26208 | biostudies-arrayexpress
TranscriptomicsTaf7l Modulates Brown Adipose Tissue Formation
Brown adipose tissue (BAT) plays an essential role in metabolic homeostasis by dissipating energy via thermogenesis through uncoupling protein 1 (Ucp1). Previously, we reported that the TATA-binding protein Associated Factor 7L (Taf7l) is an important regulator of white adipose tissue (WAT) differen...
ORGANISM(S): Mus musculus 
2014-06-03 | E-GEOD-55797 | biostudies-arrayexpress
TranscriptomicsGene Expression Profiling of Glycine max Cotyledons and Trifoliate Leaves to Determine Genes Associated with Senescence
We use RNA sequencing technology in a time course study to measure transcript abundance from three developmental stages in cotyledons and five stages in the trifoliate leaf of Glycine max to identify genes with distinct temporal patterns of expression during leaf or cotyledon development. We also ex...
ORGANISM(S): Glycine max 
2015-05-01 | E-GEOD-61857 | biostudies-arrayexpress
TranscriptomicsMicroRNAs are required for the feature maintenance and differentiation of brown adipocytes
Brown adipose tissue is specialized to burn lipids for heat generation as a natural defense against cold and obesity. Previous studies established microRNAs as essential regulators of brown adipocyte differentiation, but it remains unknown whether microRNAs are required for the feature maintenance o...
ORGANISM(S): Mus musculus 
2014-08-07 | E-GEOD-60165 | biostudies-arrayexpress
ProteomicsIdentify proteins secreted from mouse brown adipocytes
Immortalized mouse brown preadipocytes were differentiated. Conditioned medium was collected and concentrated. Proteins present in the conditioned medium were analyzed by LC-MS/MS
ORGANISM(S): Mus musculus (Mouse) 
2022-11-11 | PXD038041 | Pride
Mouse Brown adipocyte Adipokine Lc-ms/ms 
TranscriptomicsGenotyping by whole-exome sequencing of human with hereditary pheochromocytoma
Whole exome sequencing identification of Max mutations and further validation in pheochromocytoma patients
ORGANISM(S): Homo sapiens 
2012-03-01 | E-MTAB-591 | biostudies-arrayexpress
TranscriptomicsGenotyping of Cowpea using a Soybean Genome Array
Background:; Cowpea (Vigna unguiculata L. Walp) is an important food and fodder legume of the semiarid tropics and subtropics worldwide, especially in sub-Saharan Africa. High density genetic linkage maps are needed for marker assisted breeding but are not available for cowpea. A single feature poly...
ORGANISM(S): Vigna unguiculata 
2008-04-07 | E-GEOD-10284 | biostudies-arrayexpress
ProteomicsLC-MS/MS proteomic analysis of mouse brown adipose tissues
This project aims to identify the proteins present in RNA granules of brown adipose tissue upon exposure to cold challenge. Wild type C57BL/6J mice were born and raised at thermoneutrality and were then subjected to cold exposure for 90 minutes. Brown adipose tissues were collected, and the protein ...
ORGANISM(S): Mus musculus (Mouse) 
2023-11-23 | PXD044433 | Pride
Brown adipose tissue Mouse Cold challenge Rna granules 
ProteomicsApoptotic brown adipocytes enhance energy expenditure via SLC29A1-regulated extracellular inosine
Brown adipose tissue (BAT) dissipates energy and promotes cardio-metabolic health4. However, loss of BAT during obesity and aging is a principal hurdle for BAT-centered obesity therapies. So far not much is known about BAT apoptosis and signals released by apoptotic brown adipocytes. Here, untargete...
ORGANISM(S): Mus musculus (Mouse) 
2022-05-31 | PXD032153 | Pride
Bat Insoine 
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