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TranscriptomicsAutotaxin and its product lysophosphatidic acid suppress brown adipose differentiation and promote diet-induced obesity in mice
Brown adipose tissue (BAT) is a thermogenic organ that dissipates stored energy as heat to maintain body temperature in infants and small mammals. This process may also provide protection from development of diet-induced obesity. We found that the bioactive lipid mediator lysophosphatidic acid (LP...
ORGANISM(S): Mus musculus 
2011-06-01 | E-GEOD-26442 | biostudies-arrayexpress
UnknownDevelopment of a large SNPs resource and a low-density SNP array for brown trout (Salmo trutta) population genetics.
Not available
S-EPMC6631668 | biostudies-literature
TranscriptomicsGene expression profiling reveals mast cell-dependent inflammation in the meninges in early EAE.
The meninges are generally considered relatively inert tissues that house the CSF and provide protection for the brain and spinal cord. However, our previous studies using Kit mutant (Kit W/Wv) mast cell-deficient mice demonstrated that mast cells residing in the dura mater and pia mater exacerbate ...
ORGANISM(S): Mus musculus 
2013-01-01 | E-GEOD-37191 | biostudies-arrayexpress
TranscriptomicsRat Normal Cochlear Nucleus
The cochlear nucleus is the first central pathway involved in the processing of peripheral auditory activity. It is heterogeneous in neuronal populations and physiologic responses and is organized in three major subdivisions: the anterior ventral cochlear nucleus (AVCN), the posterior ventral cochl...
ORGANISM(S): Rattus norvegicus 
2005-12-31 | E-GEOD-3628 | biostudies-arrayexpress
TranscriptomicsGene expression in the right ventricle of Rattus norvegicus during development of right ventricular heart failure and treatment
Right ventricular heart failure (RVF) associated with pulmonary hypertension (PH) is characterized by a distinct gene expression pattern when compared with functional compensatory hypertrophy. Carvedilol treatment after RVF has been established reduces right ventricle (RV) hypertrophy and improves...
ORGANISM(S): Rattus norvegicus 
2013-05-06 | E-GEOD-42579 | biostudies-arrayexpress
UnknownHER2-HER3 Heterodimer Quantification by FRET-FLIM and Patient Subclass Analysis of the COIN Colorectal Trial.
Not available
S-EPMC7492762 | biostudies-literature
TranscriptomicsRiboflavin depletion impairs cell proliferation in intestinal cells: Identification of mechanisms and consequences
Microarray analysis has been applied to the cell proliferation in a human colonic cel line, Caco-2. We have shown previously that a moderate riboflavin depletion around weaning has a profound impact on the structure and function of the small intestine of the rat, which is not reversible following ri...
ORGANISM(S): Homo sapiens 
2009-03-06 | E-GEOD-15132 | biostudies-arrayexpress
UnknownOn the sources and sinks of atmospheric VOCs: an integrated analysis of recent aircraft campaigns over North America.
Not available
S-EPMC7939023 | biostudies-literature
TranscriptomicsReversible and irreversible differentiation of cardiac fibroblasts
Aim: Differentiation of cardiac fibroblasts (Fb) into myofibroblasts (MyoFb) is responsible for connective tissue buildup in myocardial remodeling. We examined reversibility of MyoFb differentiation. Methods and Results: Adult rat cardiac Fb were cultured on a plastic substratum providing mechanical...
ORGANISM(S): Rattus norvegicus 
2014-01-07 | E-GEOD-51824 | biostudies-arrayexpress
UnknownA "Dirty" Footprint: Macroinvertebrate diversity in Amazonian Anthropic Soils.
Not available
S-EPMC9292437 | biostudies-literature
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