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TranscriptomicsAge- and Obesity Induced Decline of Brown Fat Function as Consequence of Impaired miR-328 Dependent Silencing of Bace1
Activated brown adipose tissue contributes to control of energy and glucose homeostasis in rodents and humans. Defining cell-autonomous processes underlying BAT differentiation and activation may thus reveal novel therapeutic targets for obesity and type 2 diabetes mellitus intervention. Here we sho...
ORGANISM(S): Mus musculus 
2015-06-17 | E-GEOD-69913 | biostudies-arrayexpress
GenomicsPR
Pharmacogenomic response to Statins samples (Genotypes/Phenotypes)
EGAD00010000282 | EGA
GenomicsWTCCC2 Pharmacogenomic Response to Statins study
A WTCCC2 project genome-wide study for pharmacogenomic response to statins (PR) in individuals from Scotland.
EGAS00000000121 | EGA
UnknownThe complete mitochondrial DNA sequence of the pantropical earthworm Pontoscolex corethrurus (Rhinodrilidae, Clitellata): Mitogenome characterization and phylogenetic positioning.
Not available
S-EPMC5672579 | biostudies-literature
Transcriptomicsrat small intestine samples
Experiment description 1. Experimental design 1) Authors, laboratory, and contact: Xue-Lin Cui1, Patricia Soteropoulos2, Peter Tolias2, Ronaldo P. Ferraris1: 1Dept. of Pharmacology and Physiology, UMDNJ-New Jersey Medical School, Newark, NJ 07103-2714, 2Center for Applied Genomics, PHRI, 225 Warre...
ORGANISM(S): Rattus norvegicus 
2010-06-09 | E-GEOD-996 | biostudies-arrayexpress
UnknownInvestigation of relationships between urinary biomarkers of phytoestrogens, phthalates, and phenols and pubertal stages in girls.
Not available
S-EPMC2920905 | biostudies-literature
TranscriptomicsProtein Arginine Methyltransferase 6 dependent gene expression and splicing: Association with breast cancer outcomes
Protein arginine methyltransferase-6 (PRMT6) regulates steroid-dependent transcription and alternative splicing, and is implicated in endocrine system development and function, cell death, cell cycle, gene expression and cancer. Despite its role in these processes, little is known about its function...
ORGANISM(S): Homo sapiens 
2012-08-01 | E-GEOD-36542 | biostudies-arrayexpress
TranscriptomicsMolecular Profiling of Metastatic Prostate Carcinoma Reveals Substantial Inter-individual and Limited Intra-individual Diversity: Implications for Precision Oncology
Prostate cancers exhibit a spectrum of molecular aberrations of which a substantial subset are amenable to targeted therapeutics. To determine the diversity of somatic alterations present in metastasis within and between individuals we characterized the genomic landscapes of 176 tumors acquired from...
ORGANISM(S): Homo sapiens 
2015-12-18 | E-GEOD-74685 | biostudies-arrayexpress
UnknownCharacteristics, therapies, and outcomes of In-Hospital vs Out-of-Hospital cardiac arrest in patients presenting to cardiac intensive care units: From the critical care Cardiology trials network (CCCTN).
Not available
S-EPMC9899313 | biostudies-literature
UnknownTechnology-Enabled (P)rehabilitation for Patients Undergoing Cancer Surgery: A Systematic Review and Meta-Analysis.
Not available
S-EPMC12839342 | biostudies-literature
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