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TranscriptomicsSingle-cell RNA-seq of de-differentiated mammary adipocytes during lactation
Adipose tissue in the mammary gland undergoes dramatic remodeling during reproduction. Adipocytes are replaced by mammary alveolar structures during pregnancy and lactation, then reappear upon weaning. Here, we reveal that adipocytes in the mammary gland de-differentiate into Pdgfrα+ preadipocyte- a...
ORGANISM(S): Mus musculus 
2018-06-17 | E-MTAB-6818 | biostudies-arrayexpress
TranscriptomicsIn vivo LPS responses in murine splenic CD8 and CD11b DC subsets
Background: Dendritic cells (DCs) are critical for regulating CD4 and CD8 T cell immunity, controlling Th1, Th2, and Th17 bias, generating inducible Tregs, and inducing tolerance. Multiple DC subsets have been identified in the mouse that are thought to have evolved to control these different immune...
ORGANISM(S): Mus musculus 
2014-07-01 | E-GEOD-42573 | biostudies-arrayexpress
TranscriptomicsGlobal miRNA transcriptomic profiling of permanent focal ischemia in an in vivo rat model
Focal ischemia is triggered by the sudden significant reduction of blood supply to the brain, as a result of either the rupture or occlusion by thrombus/embolism of a blood vessel in the brain. Permanent focal ischemia occurred when blood supply to a specific part of the brain is impeded without rep...
ORGANISM(S): Rattus norvegicus 
2013-12-31 | E-GEOD-25556 | biostudies-arrayexpress
UnknownCohort profile: the longitudinal National Growth and Health Study (NGHS) of black and white girls from Northern California tracking how behavioural and psychosocial risk factors predict cardiovascular risk and biological ageing in midlife and in offspring.
Not available
S-EPMC10632866 | biostudies-literature
UnknownAre large clinical trials in orthopaedic trauma justified?
Not available
S-EPMC5909275 | biostudies-literature
UnknownMeta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
Not available
S-EPMC3896259 | biostudies-literature
UnknownAssociation of low-frequency and rare coding variants with information processing speed.
Not available
S-EPMC8643353 | biostudies-literature
UnknownStenting and medical therapy for atherosclerotic renal-artery stenosis.
Not available
S-EPMC4815927 | biostudies-literature
UnknownAssessment, endoscopy, and treatment in patients with acute severe ulcerative colitis during the COVID-19 pandemic (PROTECT-ASUC): a multicentre, observational, case-control study.
Not available
S-EPMC7906670 | biostudies-literature
UnknownSafety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK.
Not available
S-EPMC7723445 | biostudies-literature
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