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MetabolomicsInhibition of glycolysis and mitochondrial respiration promotes radiosensitisation of neuroblastoma and glioma cells

BACKGROUND: Neuroblastoma accounts for 7% of paediatric malignancies but is responsible for 15% of all childhood cancer deaths. Despite rigorous treatment involving chemotherapy, surgery, radiotherapy and immunotherapy, the 5-year overall survival rate of high-risk disease remai...

2022-11-30 | MTBLS858 | MetaboLights
ModelsTikidji-Hamburyan2018 - Rod phototransduction under strong illumination
Tikidji-Hamburyan2018 - Rod phototransduction under strong illumination This model is described in the article: Rods progressively escape saturation to drive visual responses in daylight conditions. Tikidji-Hamburyan A, Reinhard K, Storchi R, Dietter J, Seitter H, Davis KE, ...
MODEL1710030000 | BioModels
UnknownROR1-targeted delivery of OSU-2S, a nonimmunosuppressive FTY720 derivative, exerts potent cytotoxicity in mantle-cell lymphoma in vitro and in vivo.
Not available
S-EPMC7299545 | biostudies-literature
ProteomicsC. thermocellum dHydG Acetate LC-MS/MS
Deletion of a hydrogenase maturation factor (HydG) knocks out the assembly of mature, functioning hydrogenases to divert metabolic flux away from hydrogen production and towards ethanol. Other system-wide affects assessed.
ORGANISM(S): Clostridium thermocellum (strain DSM 1313 / LMG 6656 / LQ8) 
2016-11-03 | PXD000777 | Pride
Lc-ms/ms Sulfur Hydrogenase g deletion Acetate Fermentation Thermocellum Bioethanol Clostridium 
UnknownRandomized Open-Label Phase II Trial of Apitolisib (GDC-0980), a Novel Inhibitor of the PI3K/Mammalian Target of Rapamycin Pathway, Versus Everolimus in Patients With Metastatic Renal Cell Carcinoma.
Not available
S-EPMC5569691 | biostudies-literature
ProteomicsClostridium autoethanogenum isopropanol production via native plasmid pCA replicon
Clostridium autoethanogenum isopropanol production via native plasmid pCA replicon
ORGANISM(S): Clostridium Autoethanogenum (ncbitaxon:84023) 
2022-05-10 | MSV000089452 | MassIVE
MetabolomicsGNPS - Integrated omics analysis reveals metabolic adaptation of Clostridium thermocellum to lignocellulose-derived growth inhibitors released during the deconstruction of switchgrass
Integrated omics analysis reveals metabolic adaptation of Clostridium thermocellum to lignocellulose-derived growth inhibitors released during the deconstruction of switchgrass
ORGANISM(S): Hungateiclostridium Thermocellum (ncbitaxon:1515) 
MSV000080128 | GNPS
MetabolomicsRapid identification of species, sex and maturity by mass spectrometric analysis of animal faeces

BACKGROUND: We describe a new approach to the recovery of information from faecal samples, based on the analysis of the molecular signature generated by rapid evaporative ionisation mass spectrometry (REIMS).

RESULTS: Faecal pellets from five different r...

2022-02-03 | MTBLS1095 | MetaboLights
ProteomicsIntegrated omics analysis reveals metabolic adaptation of Clostridium thermocellum to lignocellulose-derived growth inhibitors released during the deconstruction of switchgrass
Integrated omics analysis reveals metabolic adaptation of Clostridium thermocellum to lignocellulose-derived growth inhibitors released during the deconstruction of switchgrass
ORGANISM(S): Hungateiclostridium Thermocellum (ncbitaxon:1515) 
MSV000080128 | MassIVE
GenomicsIschemic Stroke Genetics Study (ISGS)

The third leading cause of death in the United States, stroke is an acute neurological event leading to death of neural tissues. Although the majority of strokes are ischemic strokes, meaning there is oxygen deprivation to the brain, almost 20% of strokes are hemorrhagic, resulting from...

phs000102.v1.p1 | EGA
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