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GenomicNHLBI GO-ESP: Heart Cohorts Exome Sequencing Project (ISGS)

The NHLBI "Grand Opportunity" Exome Sequencing Project (GO-ESP), a signature project of the NHLBI Recovery Act investment, was designed to identify genetic variants in coding regions (exons) of the human genome (the "exome") that are associated with heart, lung and blood diseases. These and relat...

phs000546 | dbGaP
TranscriptomicsSubcellular RNA Sequencing Reveals Broad Presence of Cytoplasmic Intron-sequence Retaining Transcripts in Mouse and Rat Neurons.
Recent findings have revealed the complexity of the transcriptional landscape in mammalian cells. One recently described class of novel transcripts are the Cytoplasmic Intron-sequence Retaining Transcripts (CIRTs), hypothesized to confer post-transcriptional regulatory function. For instance, the ne...
ORGANISM(S): Mus musculus 
2013-10-15 | E-GEOD-49592 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of S. cerevisiae laboratory strain BY4743 and commercial dry active yeast
This series represents the analysis of a commercial dry active yeast (purchased locally). The genetics of this sample is unknown.
ORGANISM(S): Saccharomyces cerevisiae 
2007-10-23 | E-GEOD-1314 | biostudies-arrayexpress
ProteomicsHeat stress triggers protein secretion into the extracellular matrix of sorghum cell suspension cultures
Plants reprogram gene expression as an adaptive response to survive high temperatures. While the identity and functions of intracellular heat stress-responsive proteins have been extensively studied, the heat response of proteins secreted to the extracellular matrix is unknown. Here, we used Sorghum...
ORGANISM(S): Sorghum bicolor 
2020-10-29 | PXD021536 | Pride
Sorghum Itraq Heat stress 
TranscriptomicsRNA-Seq of six mammals
Homologous vertebrate tissues express a highly conserved set of transcribed genes; paradoxically, expression of tRNAs that are required to translate mRNAs into proteins have been reported to be divergent. To resolve this paradox, we mapped the genome-wide occupancy of pol III in primary tissues iso...
ORGANISM(S): Mus musculus 
2011-07-29 | E-MTAB-424 | biostudies-arrayexpress
ProteomicsCellular interactome of HSV-1 pUL21
The herpes simplex virus (HSV)-1 protein pUL21 is essential for efficient virus replication and dissemination. While pUL21 has been shown to promote multiple steps of virus assembly and spread, the molecular basis of its function remained unclear. Here we identify that pUL21 is a virus-encoded adapt...
ORGANISM(S): Homo sapiens (Human) 
2021-08-05 | PXD027257 | Pride
Col4a3bp Herpes simplex virus 1 Herpesvirus Protein phosphatase 1 Cert Silac Pp1 
GenomicsChIP-Seq of six mammals tissues: liver, muscle, testes with antibody against RNA polymerase III
Homologous vertebrate tissues express a highly conserved set of transcribed genes; paradoxically, expression of tRNAs that are required to translate mRNAs into proteins have been reported to be divergent. To resolve this paradox, we mapped the genome-wide occupancy of pol III in primary tissues iso...
ORGANISM(S): Homo sapiens 
2011-07-29 | E-MTAB-958 | biostudies-arrayexpress
UnknownDiversity and shifts of the bacterial community associated with Baikal sponge mass mortalities.
Not available
S-EPMC6438488 | biostudies-literature
GenomicsChIP-seq of mouse liver with no antibody to provide input sequences for ChIP experiments on C57BJ/6J mice
This experiment provides chromatin immunoprecipitation input sequences (i.e. no antibody was added during the ChIP protocol), suitable for use as input for ChIP experiments on C57BJ/6J mice.
ORGANISM(S): Mus musculus 
2011-03-01 | E-MTAB-442 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of the response of Saccharomyces cerevisiae to desiccation and rehydration: Series 3
This series represents Experiment 3 of the yeast desiccation / rehydration time course analysis. Samples include Control, 50% dry, Dry, 15 min. post rehydration, 45 min. post rehydration, 90 min. post rehydration, and 360 min. post rehydration.
ORGANISM(S): Saccharomyces cerevisiae 
2007-10-23 | E-GEOD-1313 | biostudies-arrayexpress
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