Brown adipose tissue (bat)

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Unknown (1230)
Genomics (413)
Transcriptomics (404)
Proteomics (73)
Metabolomics (18)
Other (7)
Methylation profiling (1)

Organisms

Mus musculus (394)
Bombyx mori (47)
Klebsiella pneumoniae (47)
Schizosaccharomyces pombe (47)
Streptomyces coelicolor A3(2) (47)
Human immunodeficiency virus 1 (47)
Oryza sativa Indica Group (47)
Sinorhizobium meliloti BL225C (47)
Vitis (47)
Homo sapiens (36)
Rattus norvegicus (17)
Rousettus aegyptiacus (4)
Ovis aries (3)
Sus scrofa (2)
Mus (2)
Urocitellus parryii (2)
Rhinolophus ferrumequinum (1)
Miniopterus schreibersii (1)
Myotis davidii (1)
Pteropus alecto (1)
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mixed sample (1)
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Callospermophilus lateralis (1)
Ictidomys tridecemlineatus (1)
Oryctolagus cuniculus (1)
feces metagenome (1)
human feces metagenome (1)
Fusarium sinicum (1)

Organisms

Mus musculus (278)
Homo sapiens (16)
Rattus norvegicus (5)
Urocitellus parryii (2)
Mus (2)
Peromyscus maniculatus (1)
unidentified (1)
Mus musculus domesticus (1)
Mesocricetus auratus (1)
Oryctolagus cuniculus (1)
Ovis aries (1)
gut metagenome (1)
mouse gut metagenome (1)

Repository

ENA (366)
geo (268)
biostudies-arrayexpress (189)
pride (47)
MetaboLights (18)
MassIVE (9)
iProX (7)
jPOST (6)
PAXDB (4)
ExpressionAtlas (1)
GPMDB (1)

Tissue

Brown adipose tissue (26)
Liver (9)
Brown fat cell (5)
Adipose tissue (5)
White adipose tissue (3)
Heart (3)
Brain (3)
Blood plasma (3)
Skeletal muscle (2)
Cell culture (2)
Hepatocyte (2)
Ventromedial hypothalamic nucleus (1)
Epicardial adipocyte (1)
Regulation of endothelial cell differentiation (1)
Skeletal muscle cell line (1)
Diaphragm (1)
Brown adipocyte (1)
Primary cell line cell (1)
Quadriceps (1)
Epididymal white adipose tissue (1)
Hypothalamus (1)
Spleen (1)
Kidney (1)
Macrophage (1)

Disease

Type 1 diabetes mellitus (2)
Disease free (2)
Type 2 diabetes mellitus (2)
Pre-tumoral lesion in a mouse model of human adamantinomatous craniopharyngioma (ACP) (1)
Not Available (1)
Inflammation (1)
Severe acute respiratory syndrome (1)
Obesity (1)
Cardiovascular system disease (1)

Technology Type

Mass Spectrometry (47)
Shotgun proteomics (19)
Bottom-up proteomics (13)
Mass spectrometry (10)
Mass spectrometry assay (6)
Data-dependent acquisition (6)
Data-independent acquisition (5)
Top-down proteomics (4)
SWATH MS (4)
NMR spectroscopy (2)
Gel-based experiment (2)
SRM/MRM (1)
Affinity purification coupled with mass spectrometry proteomics (1)

Instrument Platform

Illumina NovaSeq 6000 (16)
Illumina HiSeq 2500 (11)
NextSeq 500 (5)
Illumina HiSeq 4000 (4)
Liquid Chromatography MS - alternating - reverse phase (4)
Liquid Chromatography MS - alternating - hilic (4)
Illumina HiSeq 3000 (2)
Orbitrap Fusion Lumos (2)
Q Exactive (2)
Liquid Chromatography MS - alternating - reverse-phase (2)
Liquid Chromatography MS - negative - reverse-phase (2)
Liquid Chromatography MS - negative - reverse phase (2)
Liquid Chromatography MS - positive - reverse phase (2)
Illumina NovaSeq X (1)
NextSeq 2000 (1)
ACCRE (1)
NextSeq 550 (1)
Illumina HiSeq 2000 (1)
Instrument (1)
Thermo Q Exactive Plus (1)
TripleTOF 6600 (1)
TripleTOF 5600 (1)
Orbitrap Exploris 480 (1)
Orbitrap Fusion (1)
Q Exactive HF (1)
Thermo Electron FOCUS GC (1)
Liquid Chromatography MS - alternating (1)
Xevo G2 QTOF (Waters) (1)
Bruker (1)
Liquid Chromatography MS - (1)

Publication Date

2026 (64)
2025 (55)
2024 (51)
2022 (50)
2015 (44)
2023 (42)
2021 (30)
2014 (26)
2018 (23)
2019 (22)
2020 (20)
2016 (20)
2013 (20)
2017 (16)
2012 (16)
2010 (15)
2011 (11)
2008 (9)
2007 (6)
2009 (4)
2006 (1)
2005 (1)
2004 (1)

UNIPROT ID/AC

LEG12_MOUSE (3)
CLIC3_MOUSE (3)
PPCT_MOUSE (3)
M1IP1_MOUSE (3)
HPCL4_MOUSE (3)
MGMT_MOUSE (3)
ATP7A_MOUSE (3)
SORC2_MOUSE (3)
ANCHR_MOUSE (3)
ELMO2_MOUSE (3)
CEPT1_MOUSE (3)
SHPK_MOUSE (3)
TARG1_MOUSE (3)
Q8K094_MOUSE (3)
DDHD1_MOUSE (3)
PP4R2_MOUSE (3)
RBNS5_MOUSE (3)
SIK2_MOUSE (3)
PGGHG_MOUSE (3)
COQ8B_MOUSE (3)
ARSA_MOUSE (3)
AL3B2_MOUSE (3)
VPS16_MOUSE (3)
JAK1_MOUSE (3)
WDR5_MOUSE (3)
TCPR1_MOUSE (3)
TBL2_MOUSE (3)
CMTR1_MOUSE (3)
RL18A_MOUSE (3)
CHAC2_MOUSE (3)

CHEBI ID

CHEBI:27266 (3)
CHEBI:25017 (3)
CHEBI:16610 (2)
CHEBI:15356 (2)
CHEBI:15354 (2)
CHEBI:22660 (2)
CHEBI:24898 (2)
CHEBI:22653 (2)
CHEBI:16811 (2)
CHEBI:27570 (2)
CHEBI:17750 (2)
CHEBI:27897 (2)
CHEBI:29016 (2)
CHEBI:16919 (2)
CHEBI:28300 (2)
CHEBI:15741 (2)
CHEBI:25094 (2)
CHEBI:17822 (2)
CHEBI:30887 (2)
CHEBI:26271 (2)
CHEBI:18186 (2)
CHEBI:18012 (2)
CHEBI:16750 (2)
CHEBI:30769 (2)
CHEBI:17345 (2)
CHEBI:28044 (2)
CHEBI:6650 (2)
CHEBI:18237 (2)
CHEBI:20067 (2)
CHEBI:17596 (2)

Metabolite Name

PE(16:0/0:0) (2)
Formiminoglutamic acid (2)
Valine (2)
Farnesyl acetone (2)
UMP (2)
CMP (2)
DTMP (2)
Cholic acid (2)
Hypoxanthine (2)
Gluconic acid (2)
Succinate (2)
GMP (2)
Fumarate (2)
ATP (2)
AMP (2)
4-Hydroxybenzaldehyde (2)
L-Tyrosine (2)
Leucine (2)
5-Hydroxyindoleacetic acid (2)
(S)-(-)-Perillyl alcohol (2)
Sphingosine (2)
Choline (2)
Beta-L-Fucose (1)
Xi-2-Methyl-1,3-oxathiane (1)
MEPHENOXALONE (1)
Ile Ala Lys (1)
Asp Phe Lys (1)
DG(PGJ2/0:0/i-17:0) (1)
Hydroxycarbonate (1)
Alpha-Ionene (1)

First Public Date

2025 (59)
2026 (54)
2024 (48)
2022 (43)
2023 (36)
2021 (24)
2014 (20)
2018 (18)
2020 (16)
2019 (15)
2015 (13)
2017 (12)
2016 (6)
2013 (2)

Modification

4-tetrahydrothiazine-3-carboxylic acid (1)

Study type

Transcription profiling by array (113)
RNA-seq of coding RNA (36)
Animal - High-throughput sequencing (9)
ChIP-seq (5)
RNA-seq of non coding RNA (5)
RNA-seq of coding RNA from single cells (4)
RNA-seq of total RNA (4)
Single nucleus RNA sequencing (3)
Unknown experiment type (2)
Animal - Single-cell sequencing (2)
High-throughput sequencing (1)
MicroRNA profiling by high throughput sequencing (1)
Spatial transcriptomics by high-throughput sequencing (1)
Comparative genomic hybridization by array (1)
Other (1)
MicroRNA profiling by array (1)

Release Date

2022 (162)
2021 (137)
2020 (119)
2025 (113)
2023 (108)
2024 (107)
2018 (104)
2019 (103)
2015 (85)
2017 (79)
2016 (64)
2014 (56)
2013 (45)
2012 (39)
2026 (28)
2010 (20)
2011 (16)
2008 (12)
2009 (9)
2007 (8)
2006 (2)
2005 (1)
1999 (1)

Lab affiliation

Howard Hughes Medical Institute Beth Israel Deaconess Medical Center Harvard Medical School (2)
Helmholtz Diabetes Center Munich (1)
Seoul National University, School of Biological Sciences (1)
Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, 28029, Spain (1)
Cellular and Molecular Pharmacology, Quantitative Biosciences Institute, Gladstone Institutes, University of California San Francisco, CA, USA (1)
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA. Department of Cell Biology, Harvard Medical School, Boston, MA, USA. (1)
Institue of Molecular Systems Biology ETH Zurich, Switzerland (1)
Italian National Institute of Health - Department of Neuroscience (1)
1 Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA 2 Department of Cell Biology, Harvard Medical School, Boston, MA, USA (1)
Department of Animal Sciences, Purdue University, West Lafayette, IN 47907, USA Center for Cancer Research Purdue University, West Lafayette, IN 47907, USA (1)
John van Geest Cancer Research Centre Nottingham Trent University Nottingham, UK (1)
Profeesor Department of Biochemistry and Molecular Biology University of Southern Denmark Odense, Denmark (1)
School of Life and Environmental Sciences, Faculty of Science, University of Sydney. (1)
Helmholtz Diabetes Center (1)
Department of Physiology and Pharmacology, Karolinska Institutet, Solna, Sweden. (1)
University of Cologne (1)
Division of Cardiovascular Medicine, Department of Medicine, Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA. Fraternal Order of Eagles Diabetes Research Center, Pappajohn Biomedical Institute, and Heart and Vascular Center, University of Iowa, University of Iowa, Iowa City, Iowa, USA. (1)
Cell Biology and Physiology, Washington University in St. Louis (1)
Associate Professor Department of Cell and Developmental Biology University of Pennsylvania Perelman School of Medicine (1)
Department of Biology, University of Rome Tor Vergata, Rome, Italy (1)
Head of Proteomics Plattform D-HEST HPT D 77 Auguste-Piccard-Hof 1 8093 Zürich Switzerland (1)
Brandenburg University of Technology Cottbus-Senftenberg (1)
Department of Pathology, Section on Comparative Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States (1)
1 Department of Chemistry, University of Wisconsin-Madison, Madison, WI, USA 2 Department of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, WI, USA 3 Morgridge Institute for Research, Madison, WI, USA 4 National Center for Quantitative Biology of Complex Systems, Madison, WI, USA (1)
1Rosalind & Morris Goodman Cancer Institute, McGill University, Montreal, QC, H3A 1A3, Canada 2Department of Biochemistry, McGill University, Montreal, QC, H3G 1Y6, Canada (1)
Proteomics Unit, CNIC; Madrid, Spain (1)
1Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research (A*STAR), Singapore 2 Lee Kong Chian School of Medicine, Nanyang Technological University (NTU), Singapore 3 Cardiovascular and Metabolic Disorders Program, Duke-NUS Medical School, Singapore 4Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore 5 Department of Endocrinology, Tan Tock Seng Hospital (TTSH), Singapore (1)
Department of Biochemistry and Molecular Biomedicine and Institute of Biomedicine 10 (IBUB), University of Barcelona, Barcelona, Spain CIBER “Fisiopatología de la Obesidad y Nutrición”, Instituto de Salud Carlos III, Madrid, Spain (1)
Nestlé Research – Nestlé Institute of Food Safety & Analytical Sciences (1)
Boston University School of Medicine (1)

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Absence of MCJ/DnaJC15 promotes brown adipose tissue thermogenesis

Obesity poses a global health challenge, demanding a deeper understanding of adipose tissue (AT) and its mitochondria. This study describes the role of the mitochondrial protein Methylation-controlled J protein (MCJ/DnaJC15) in orchestrating brown adipose tissue (BAT) thermogenesis. Here we show how...

2024-10-31 | MTBLS11505 | MetaboLights

Mouse Brown Adipose Tissue Lipidomics under Cold and Dietary Fat Interventions

This study investigates lipidomic remodeling in mouse brown adipose tissue under a 2 × 3 experimental design involving environmental condition and dietary fatty acid composition. Mice were maintained at room temperature with ad libitum feeding or exposed to 4°C cold conditions with 70% calorie restr...

2026-06-01 | MTBLS14642 | MetaboLights

Angiopoietin-like 4 governs diurnal lipoprotein lipase activity in brown adipose tissue.

OBJECTIVE: Brown adipose tissue (BAT) burns fatty acids (FAs) to produce heat, and shows diurnal oscillation in glucose and triglyceride (TG)-derived FA-uptake, peaking around wakening. Here we aimed to gain insight in the diurnal regulation of metabolic BAT activity.

2023-11-15 | MTBLS4082 | MetaboLights

A metabolomic study of adipose tissue in mice with a disruption of the circadian system

Adipose tissue functions in terms of energy homeostasis as a rheostat for blood triglyceride, regulating its concentration, in response to external stimuli. In addition it acts as a barometer to inform the central nervous system of energy levels which can vary dramatically between meals and accor...

2017-10-27 | MTBLS380 | MetaboLights

A metabolomic study of adipose tissue in mice with a disruption of the circadian system

2017-10-27 | MTBLS390 | MetaboLights

A metabolomic study of adipose tissue in mice with a disruption of the circadian system

2017-10-27 | MTBLS382 | MetaboLights

Taf7l Modulates Brown Adipose Tissue Formation

Brown adipose tissue (BAT) plays an essential role in metabolic homeostasis by dissipating energy via thermogenesis through uncoupling protein 1 (Ucp1). Previously, we reported that the TATA-binding protein Associated Factor 7L (Taf7l) is an important regulator of white adipose tissue (WAT) differen...

ORGANISM(S): Mus musculus

2014-06-03 | E-GEOD-55797 | biostudies-arrayexpress

Mus musculus brown adipose tissue histone proteoforms

Histones were isolated from brown adipose tissue and liver from mice housed at 28, 22, or 8 C. Quantitative top- or middle-down approaches were used to quantitate histone H4 and H3.2 proteoforms. See published article for complimentary RNA-seq and RRBS datasets.

ORGANISM(S): Mus Musculus (ncbitaxon:10090)

2023-06-05 | MSV000092105 | MassIVE

Brown-fat-mediated tumour suppression by cold-altered global metabolism

Glucose uptake is essential for cancer glycolysis and is involved in non-shivering thermogenesis of adipose tissues. Most cancers use glycolysis to harness energy for their infinite growth, invasion and metastasis. Activation of thermogenic metabolism in brown adipose tissue (BAT) by cold an...

2022-08-12 | MTBLS4856 | MetaboLights

A methyltransferase EHMT1 controls brown adipose cell fate and adaptive thermogenesis through a PRDM16 complex

Brown adipose tissue (BAT) dissipates chemical energy in the form of heat, as a defense against hypothermia and obesity. Current evidence indicates that brown adipocytes arise from Myf5+-dermotomal precursors through the action of a PRDM16-C/EBP-_ transcriptional complex; however, the underlying mec...

ORGANISM(S): Mus musculus

2013-11-07 | E-MTAB-1704 | biostudies-arrayexpress

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