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UnknownHarmonizing results of ataxia rating scales: mFARS, SARA, and ICARS.
Not available
S-EPMC9735370 | biostudies-literature
TranscriptomicsTranscription profiling of Neuropeptide S Receptor 1-A (NPSR1-A) transfected human epithelial kidney cells stimulated with neuropeptide S to identify downstream targets
The purpose of this study was to identify downstream gene targets regulated by Neuropeptide S Receptor 1 (NPSR1) upon NPS stimulation. To do this we used human epithelial kidney (HEK)-293H cell lines stable transfected with NPSR1-A and stimulated with NPS for 6 hours. Two controls were used: NPS sti...
ORGANISM(S): Homo sapiens 
2006-08-24 | E-MEXP-829 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human adenocarcinoma cell line A549 over-expressing ELMOD2
ELMOD2 cDNA from the IMAGE clone 3897166 was cloned into the pDsRed-Monomer-N1 expression vector. ELMOD2 was overexpressed in the A549(adenomcarcinoma)cell line and cells transfected with empty vector were considered controls. Transcript profiles were compared with the Affymetrix Hgu133plus2 arrays....
ORGANISM(S): Homo sapiens 
2009-12-07 | E-MEXP-1838 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse cells expressing tet inducible LhX2, withdrawal of LHX2 over time was analysed
Expression of the lim-homeodomain transcription factor is required for sustained maintenance of heamatopoietic stem cell like cells in undifferentiated form durng in vitro culturing. Cell lines were created from the mouse embryonic stem (ES) cell line, Ainv15. The gene Lhx2 was introducted into thes...
ORGANISM(S): Mus musculus 
2005-12-19 | E-MEXP-431 | biostudies-arrayexpress
UnknownReduced cerebello-cerebral functional connectivity correlates with disease severity and impaired white matter integrity in Friedreich ataxia.
Not available
S-EPMC10130106 | biostudies-literature
TranscriptomicsTranscription profiling twenty eight growth restricted patients (including twenty two with Silver-Russel syndrome) and their parents
We studied twenty-eight growth restricted patients (twenty-two with Silver-Russell syndrome, OMIM#180860) and their parents with the Affymetrix 250K Sty SNP microarray. All patients were molecularly undefined, and thus the aim was to look for copy number alterations that might contribute to the grow...
ORGANISM(S): Homo sapiens 
2009-09-06 | E-MTAB-56 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of non-obese diabetic (NOD) mice with or without the scid mutation and BDC2.5 TCR gene knock-in to study T-cell mediated B-cell damage and repair
Dynamic interaction between T-cell mediated beta-cell damage and beta-cell repair in the run up to autoimmune diabetes of the NOD mice.
ORGANISM(S): Mus musculus 
2006-10-03 | E-CBIL-18 | biostudies-arrayexpress
TranscriptomicsDual RNA-seq of parasite and host reveals gene expression dynamics during filarial worm-mosquito interactions
Parasite biology, by its very nature, cannot be understood without integrating it with that of the host, nor can the host response be adequately explained without considering the activity of the parasite. However, due to experimental limitations, molecular studies of parasite-host systems have been ...
ORGANISM(S): Aedes aegypti 
2014-04-15 | E-GEOD-53664 | biostudies-arrayexpress
UnknownA Phase II, Double-Blind, Randomized, Placebo-Controlled, Multicenter Study Evaluating the Efficacy and Safety of Alpha-1 Antitrypsin (AAT) (Glassia®) in the Treatment of Recent-Onset Type 1 Diabetes.
Not available
S-EPMC6928874 | biostudies-literature
TranscriptomicsBrugia pahangi mature vs immature microfilariae
Filarial nematodes are arthropod-borne nematodes that cause a variety of economically important diseases such as onchocerciasis (river blindness), lymphatic filariasis, and heartworm disease. The most widespread filarial disease of humans is lymphatic filariasis, caused by worms in the genera Wuche...
ORGANISM(S): Brugia pahangi 
2010-05-22 | E-GEOD-14939 | biostudies-arrayexpress
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