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TranscriptomicsCandida albicans Nitrogen Response
To infer transcriptional networks of nitrogen utilization , Candida albicans was exposed to nitrogen starvation for four hours and then offered arginine or BSA as sole nitrogen source. Time-series transcription data was obtained from both the starvation and the feeding periods, and the response to d...
ORGANISM(S): Candida albicans 
2014-04-02 | E-MTAB-2171 | biostudies-arrayexpress
TranscriptomicsResponse of Candida albicans to taurocholate
Presence of taurocholate (TC), a constituent of bile, confers resistance of Candida albicans to antifungals like Caspofungin and Amphotericin B. Transcriptional profiles in presence and absence of TC were compared to determine whether an upregulation of known resistance genes is responsible for this...
ORGANISM(S): Candida albicans 
2017-02-15 | E-MTAB-5277 | biostudies-arrayexpress
TranscriptomicsMicroarray of Candida albicans treated with sublethal concentrations of the antifungal Jagaricin
Candida albicans were treated with a sublethal concentration of the antifungal Jagaricin for either a short time (30 min) or until an OD of 0.5 (indicating log growth) was reached. Controls were grown without any antifungal to determine cellular reactions to the compound.
ORGANISM(S): Candida albicans 
2019-06-14 | E-MTAB-7718 | biostudies-arrayexpress
MetabolomicsAntibiotics create a shift from mutualism to competition in human gut communities with a longer-lasting impact on fungi than bacteria

Background

Antibiotic treatment has a well-established detrimental effect on the gut bacterial composition, but effects on the fungal community are less clear. Bacteria in the lumen of the gastrointestinal tract may limit fungal colonization and invasion. Antibiotic drugs t...

2020-09-28 | MTBLS1846 | MetaboLights
TranscriptomicsMicroevolution of Candida albicans in macrophages restores filamentation in a nonfilamentous mutant
Following antifungal treatment, Candida albicans, and other human pathogenic fungi can undergo microevolution, which leads to the emergence of drug resistance. However, the capacity for microevolutionary adaptation of fungi goes beyond the development of drug resistance. Here we used an experimental...
ORGANISM(S): Candida albicans 
2015-03-31 | E-GEOD-56174 | biostudies-arrayexpress
TranscriptomicsMicroarray analyses of C. albicans sak1 deletion mutant in complex liquid medium (YPD)
Sak1 (orf19.3840) of Candida albicans was found to be a kinase which phosphorylates and thereby activates Snf1, a highly conserved regulator of nutrient stress responses. Accordingly, a sak1 deletion mutant failed to grow on many alternative (i.e., non-glucose) carbon sources, but also showed a fila...
ORGANISM(S): Candida albicans 
2017-05-02 | E-MTAB-5415 | biostudies-arrayexpress
TranscriptomicsMicroarray experiment of Candida albicans treated with synthetic peptides
To investigate the mode of action of a novel class of antifungal synthtic acrylamide peptides, the pathogenic yeast, Candida albicans, was exposed to sublethal doses of peptides with different structures. The experiments include the most effective structure, LH, peptides with no antifungal effects (...
ORGANISM(S): Candida albicans 
2024-06-18 | E-MTAB-13294 | biostudies-arrayexpress
TranscriptomicsLong-term exposure of Candida glabrata to human monocyte-derived macrophages, with long-term medium growth controls
Candida glabrata were kept within human moncoyte-derived macrophages (MDM) for up to seven days to investigate the transcriptome of long-term residence within phagosomes. Samples were taken after 6h and 1, 2, 4, and 7 days. To control for general starvation, long-term exposure data for the growth me...
ORGANISM(S): Candida glabrata 
2023-05-31 | E-MTAB-11801 | biostudies-arrayexpress
TranscriptomicsInteractions of Candida glabrata with human macrophages
Effect of interaction with human macrophages on the transcriptional profile of Candida glabrata
ORGANISM(S): Candida glabrata 
2011-10-31 | E-MEXP-2973 | biostudies-arrayexpress
TranscriptomicsCandida glabrata response to pH change
Transcriptional profiles of Candida glabrata exposed to two different pH values, 4.5 and 7, in complex medium.
ORGANISM(S): Candida glabrata 
2011-10-31 | E-MEXP-2974 | biostudies-arrayexpress
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