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Cut-out switch model Membrane identity and GTPase cascades regulated by toggle and cut-out switches Perla Del Conte-Zerial, Lutz Brusch, Jochen C Rink, Claudio Collinet, Yannis Kalaidzidis, Marino Zerial, and Andreas Deutsch: ...
2024-09-02 | BIOMD0000000174 | BioModels
deBack2012 - Lineage Specification in Pancreas Development This model of two neighbouring pancreas precursor cells, describes the exocrine versus endocrine lineage specification process. To account for the tissue scale patterns, this couplet model has been extended to hundreds of c...
2024-09-02 | BIOMD0000000435 | BioModels
This model describes the activation of immediate early genes such as cFos after EGF or heregulin (HRG) stimulation of the MAPK pathway. Phosphorylated cFos is a key transcription factor triggering downstream cascades of cell fate determination. The model can explain how the switch-like response of p...
2024-09-02 | BIOMD0000000251 | BioModels
The model explores the establishment and stability of the wildtype polarity pattern in planarian flatworms. Initial conditions for A and M fields are chosen as arbitrarily perturbed to demonstrate stability of the wild type pattern. A represents the A/P polarization system, M represents the M/L pola...
2021-10-05 | MODEL2107170001 | BioModels
This spatio-temporal model explores tissue polarity re-organization during planarian double-head formation upon regeneration with beta-catenin-1 RNAi treatment. Initial conditions for A and M polarity fields are chosen near the wild type pattern and the first 100 time steps are used to establish the...
2021-10-06 | MODEL2110050001 | BioModels
Morpheus model of spatio-temporal liver zonation from Wnt-Hh crosstalk
2020-11-27 | 759 | FAIRDOMHub
Morpheus model of spatio-temporal Smo regulation in response to Hh signaling
2018-06-08 | 321 | FAIRDOMHub
Spatio-temporal dynamics of Rab5 domains on the membrane of early endosomes
2018-06-08 | 322 | FAIRDOMHub
Morpheus: open source modelling and simulation framework for multicellular systems
2018-06-08 | 320 | FAIRDOMHub
Morpheus model of spatio-temporal YAP/Hippo pathway activation during liver regeneration
2020-11-27 | 760 | FAIRDOMHub
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