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GenomicsExome sequencing in classic Hairy cell leukaemia reveals widespread variation in acquired somatic mutations between individual tumours apart from the signature BRAF V(600)E lesion
Whole exome sequencing of 5 HCLc tumor-germline pairs. Genomic DNA from HCLc tumor cells and T-cells for germline was used. Whole exome enrichment was performed with either Agilent SureSelect (50Mb, samples S3G/T, S5G/T, S9G/T) or Roche Nimblegen (44.1Mb, samples S4G/T and S6G/T). The resulting exom...
ORGANISM(S): Homo sapiens 
2016-02-01 | E-MTAB-4313 | biostudies-arrayexpress
ProteomicsMapping subcellular localizations of unannotated microproteins with MicroID
Proteogenomic and ribosome profiling identification of translated small open reading frames have revealed thousands of microproteins, or polypeptides of less than 100 amino acids, that were previously invisible to geneticists. However, the vast majority of microproteins remain uncharacterized in mol...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2022-08-01 | PXD033067 | Pride
Microprotein  proximity-dependent biotinylation 
TranscriptomicsRegulation of GLI underlies a role for BET bromodomains in pancreatic cancer growth and the tumor microenvironment
Pancreatic ductal adenocarcinoma (PDAC) is extraordinarily chemoresistant and the abundant stromal content of these tumors contributes to the ineffective treatment of this disease. While the genetic alterations of PDAC have been well characterized, the epigenetic pathways regulating PDAC remain, fo...
ORGANISM(S): Homo sapiens 
2016-09-08 | E-GEOD-55209 | biostudies-arrayexpress
UnknownNutrition and obesity in under-represented population (NOURISH): study protocol to examine the effect of restricted and unrestricted financial benefits on infant food insecurity, growth, and nutrition.
Not available
S-EPMC12918438 | biostudies-literature
UnknownPharmacotherapy, alternative and adjunctive therapies for eating disorders: findings from a rapid review.
Not available
S-EPMC10327007 | biostudies-literature
UnknownCombination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer.
Not available
S-EPMC6484853 | biostudies-literature
UnknownThe implementation of tuberculosis preventive therapy in HIV care clinics in Africa, Asia and Latin America: a multiregional site survey.
Not available
S-EPMC12853508 | biostudies-literature
UnknownChronic kidney disease, cerebral blood flow, and white matter volume in hypertensive adults.
Not available
S-EPMC4818564 | biostudies-literature
UnknownEfficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine.
Not available
S-EPMC7787219 | biostudies-literature
UnknownElective surgery cancellations due to the COVID-19 pandemic: global predictive modelling to inform surgical recovery plans.
Not available
S-EPMC7272903 | biostudies-literature
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