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ProteomicsThe interactome of BTN3A1 (Butyrophilin Subfamily 3 Member A1)
In this study we dissected the BTN3A1 interactome before or after the treatment with pamidronate to gain mehcanistic insights into the gamma9/delta2 T cell dependent recognition of target cells. Our approach relied on affinity purification couple with mass spectrometry from a BTN3A knock-out cell li...
ORGANISM(S): Homo sapiens (Human) 
2020-06-05 | PXD018055 | Pride
Btn3a1 Ap-ms 
GenomicsUpregulation of BTN3A1 on CD14+ cells promotes Vγ9Vδ2 T cells activation in psoriasis vulgaris
Upregulation of BTN3A1 on CD14+ cells promotes Vγ9Vδ2 T cells activation in psoriasis vulgaris
PRJNA725400 | ENA
TranscriptomicsUpregulation of BTN3A1 on CD14+ cells promotes Vγ9Vδ2 T cells activation in psoriasis vulgaris
Vγ9Vδ2 T cells play an important role in the development and progression of psoriasis vulgaris (PV), but how they promote skin inflammation and the molecular mechanisms underlying Vγ9Vδ2 T cell dysfunction are poorly understood. Here, we show that circulating Vγ9Vδ2 T cells are decreased and exhibit...
ORGANISM(S): Homo sapiens 
2022-11-09 | GSE173387 | GEO
UnknownBTN3A1 governs antitumor responses by coordinating αβ and γδ T cells.
Not available
S-EPMC7646930 | biostudies-literature
UnknownBTN3A1 promotes tumor progression and radiation resistance in esophageal squamous cell carcinoma by regulating ULK1-mediated autophagy.
Not available
S-EPMC9684582 | biostudies-literature
UnknownUp-regulation of BTN3A1 on CD14+ cells promotes Vγ9Vδ2 T cell activation in psoriasis.
Not available
S-EPMC9636952 | biostudies-literature
UnknownPhosphoantigen-induced conformational change of butyrophilin 3A1 (BTN3A1) and its implication on Vγ9Vδ2 T cell activation.
Not available
S-EPMC5584448 | biostudies-literature
UnknownBTN3A1 Discriminates γδ T Cell Phosphoantigens from Nonantigenic Small Molecules via a Conformational Sensor in Its B30.2 Domain.
Not available
S-EPMC6558274 | biostudies-literature
UnknownActivation of human γδ T cells by cytosolic interactions of BTN3A1 with soluble phosphoantigens and the cytoskeletal adaptor periplakin.
Not available
S-EPMC4337483 | biostudies-literature
UnknownBTN3A1 expressed in cervical cancer cells promotes Vγ9Vδ2 T cells exhaustion through upregulating transcription factors NR4A2/3 downstream of TCR signaling.
Not available
S-EPMC11439235 | biostudies-literature
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