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TranscriptomicsTranscription profiling of human tetracycline-regulated cell line expressing an NF-kB inhibitor to systematically identify NF-kB dependent genes
TNF time course series of HelA tet off cells cultured in presence or absence of Dox; TNF is a pro-inflammatory cytokine that controls expression of inflammatory genetic networks. Although the Nuclear Factor-kB (NF-kB) pathway is crucial for mediating cellular TNF responses, the complete spectrum of...
ORGANISM(S): Homo sapiens 
2007-09-07 | E-GEOD-2624 | biostudies-arrayexpress
ProteomicsMARTRE family proteins negatively regulate CCR4-NOT activity to protect poly(A) tail length and promote translation of maternal mRNA
Proteomic dataset generated in the project for study the molecular function of MARTRE proteins
ORGANISM(S): Mus Musculus 
2024-11-25 | PXD051636 |
UnknownEstablishment of a Triplex qPCR Assay for Differentiating Highly Virulent Genotype I Recombinant Virus From Low-Virulence Genotype I and Genotype II African Swine Fever Viruses Circulating in China.
Not available
S-EPMC12017118 | biostudies-literature
GenomicsCohesin and CTCF Differentially Affect the Chromatin Architecture and Gene Expression in Human Cells
Recent studies of genome-wide chromatin interactions have revealed that the human genome is partitioned into many self-associating topological domains. The boundary sequences are enriched for binding sites of CTCF and the cohesin complex, implicating these two factors in the establishment or mainten...
ORGANISM(S): Homo sapiens 
2013-12-16 | E-GEOD-44267 | biostudies-arrayexpress
TranscriptomicsMolecular Determinants for RNA Polymerase II Elongation Rate and Acceleration
Recent studies reveal a striking phenomenon that RNA Polymerase II (Pol II) appears to travel on gene body in an accelerated fashion, but the mechanism has remained unknown. We performed synchronized transcription coupled with deep sequencing, observing an inverse relationship between initial rate ...
ORGANISM(S): Homo sapiens 
2015-12-31 | E-GEOD-66021 | biostudies-arrayexpress
TranscriptomicsEndothelin-1 supports clonal derivation and expansion of cardiovascular progenitors derived from human embryonic stem cells
Coronary arteriogenesis is a central step in cardiogenesis, requiring coordinated generation and integration of endothelial (EC) and vascular smooth muscle cells (SM). At present, it is unclear whether the cell fate program of cardiac progenitors to generate complex muscular or vascular structures i...
ORGANISM(S): Homo sapiens 
2015-12-15 | E-GEOD-75985 | biostudies-arrayexpress
UnknownEffects of empagliflozin on quality of life and healthcare use and costs in chronic kidney disease: a health economic analysis of the EMPA-KIDNEY trial.
Not available
S-EPMC12274867 | biostudies-literature
UnknownFrailty, Multimorbidity, and Polypharmacy: Exploratory Analyses of the Effects of Empagliflozin from the EMPA-KIDNEY Trial.
Not available
S-EPMC11390031 | biostudies-literature
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