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MetabolomicsEffects of Yulin Tong Bu formula on modulating gut microbiota and fecal metabolite interactions in mice with polycystic ovary syndrome

BACKGROUND: Polycystic ovarian syndrome (PCOS) is a common endocrine disorder characterized by hyperandrogenism, ovarian dysfunction and polycystic ovarian morphology. Gut microbiota dysbiosis and metabolite are associated with PCOS clinical parameters. Yulin Tong Bu formula (YLT...

2023-02-02 | MTBLS6736 | MetaboLights
MetabolomicsBisphenol mixture-induced DGKB downregulation promotes premature human neurogenesis through the activation of MAPK pathway

The widespread industrial transition from bisphenol A (BPA) to structural analogs such as BPS, BPE, and BPAF has raised significant concerns regarding their potential health risks. However, their neurodevelopmental risks and underlying molecular mechanisms, particularly when present as complex m...

2026-09-29 | MTBLS15671 | MetaboLights
UnknownGenome-wide identification and expression analysis of proline synthesis and catabolism genes in kiwifruit: exploring the role of <i>AcP5CS1</i> in salt tolerance.
Not available
S-EPMC12441012 | biostudies-literature
ProteomicsOptimization of Protein UFMylation Modification Method and Its Application in Substrate Identification in Human Cells
In this study, we generated the UFSP1KO/UFSP2KO HEK293T cell line and validated it as the most suitable cellular model for the screening, identification, and confirmation of UFMylated substrate proteins. Furthermore, exogenous expression of the E3 ligase components UFL1 and DDRGK1 significantly enha...
ORGANISM(S): Homo sapiens (Human) 
2026-03-30 | PXD070408 | Pride
Ufsp Ufmylation Ufl1 Ddrgk1 Substrate 
UnknownAssessment of pulmonary infectious disease treatment with Mongolian medicine formulae based on data mining, network pharmacology and molecular docking.
Not available
S-EPMC9476772 | biostudies-literature
UnknownPump-free SERS microfluidic chip based on an identification-competition strategy for ultrasensitive and efficient simultaneous detection of liver cancer-related microRNAs.
Not available
S-EPMC11563321 | biostudies-literature
UnknownIdentification of MX2 as a Novel Prognostic Biomarker for Sunitinib Resistance in Clear Cell Renal Cell Carcinoma.
Not available
S-EPMC8299280 | biostudies-literature
UnknownComprehensive investigation into cuproptosis in the characterization of clinical features, molecular characteristics, and immune situations of clear cell renal cell carcinoma.
Not available
S-EPMC9582538 | biostudies-literature
UnknownExploring white matter functional networks in children with attention-deficit/hyperactivity disorder.
Not available
S-EPMC7660033 | biostudies-literature
UnknownCCLHunter: An efficient toolkit for cancer cell line authentication.
Not available
S-EPMC10568302 | biostudies-literature
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