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TranscriptomicsRNAseq of primary human monocyte derived macrophages (MDM) and differentiated THP-1 macrophages exposed to graphene-related (nano)materials (GRMs)
Occupational and consumer exposure to GRMs will increase but their impact on human health is still largely unknown. We sought to perform a transcriptome comparison of the bioresponses of MDM and THP-1 macrophages exposed to 5 or 20 µg/ml graphene oxide (GO) or graphene nanoplatelets (GNP) for 6 and ...
ORGANISM(S): Homo sapiens 
2023-02-01 | E-MTAB-10099 | biostudies-arrayexpress
ProteomicsNanoparticles dysregulate the human placental sNanoparticles dysregulate the human placental secretome with consequences on angiogenesis and vascularizationecretome with consequences on angiogenesis and vascularization
Secretomics analysis of conditioned media from first trimester/term human placental explant cultures after exposure to SiO2, TiO2 nanoparticles (NPs) (25 μg/mL) or diesel exhaust particles (DEPs, 0.45 μg/mL)using LC-MS/MS based label-free quantification (LFQ) analysis.
ORGANISM(S): Homo sapiens (Human) 
2024-05-21 | PXD047037 | Pride
Neurodevelopment Nanoparticles Angiogenesis Developmental toxicity Secretome Placenta 
TranscriptomicsNanotoxicogenomic study of ZnO and TiO2 responses (Affymetrix)
A comprehensive in vitro assessment of two commercial metal oxide nanoparticles, TiO2 and ZnO, was performed using human monocyte-derived macrophages (HMDM), monocyte-derived dendritic cells (MDDC), and T cell leukemia-derived cell line (Jurkat). TiO2 nanoparticles were found to be non-toxic whereas...
ORGANISM(S): Homo sapiens 
2013-07-25 | E-GEOD-39330 | biostudies-arrayexpress
UnknownLabel-free detection of uptake, accumulation, and translocation of diesel exhaust particles in ex vivo perfused human placenta.
Not available
S-EPMC8130319 | biostudies-literature
UnknownHyperandrogenism? Increased 17, 20-Lyase Activity? A Metanalysis and Systematic Review of Altered Androgens in Boys and Girls with Autism.
Not available
S-EPMC8620117 | biostudies-literature
UnknownUncovering Cryptic Parasitoid Diversity in Horismenus (Chalcidoidea, Eulophidae).
Not available
S-EPMC4564207 | biostudies-literature
UnknownTranscriptome-wide detection of differentially expressed coding and non-coding transcripts and their clinical significance in prostate cancer.
Not available
S-EPMC3431106 | biostudies-literature
UnknownInvestigating the effects of differently produced synthetic amorphous silica (E 551) on the integrity and functionality of the human intestinal barrier using an advanced in vitro co-culture model.
Not available
S-EPMC7904742 | biostudies-literature
TranscriptomicsDiscovery and validation of a novel expression signature for recurrence in high-risk bladder cancer post-cystectomy
Purpose: Selecting muscle-invasive bladder cancer patients for adjuvant therapy is currently based on clinical variables with limited power. We hypothesized that genomic-based signatures can outperform clinical models to identify patients at higher risk. Method:Transcriptome-wide expression profiles...
ORGANISM(S): Homo sapiens 
2014-10-27 | E-GEOD-57933 | biostudies-arrayexpress
UnknownDe Novo Mutations in YWHAG Cause Early-Onset Epilepsy.
Not available
S-EPMC5544417 | biostudies-literature
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