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MetabolomicsBifidobacterium bifidum-derived nanoparticles attenuate alcoholic liver disease via enhanced hepatic phagocytosis and gastrointestinal homeostasis
Alcohol-associated liver disease (ALD) has limited therapeutic options due to its complex pathogenesis. This study demonstrates the ALD-protective effects of extracellular nanoparticles derived from Bifidobacterium bifidum (BNPs), focusing on the novel concept of gut microbiota-derived nanoparticles...
2025-06-19 | MTBLS12612 | MetaboLights
MetabolomicsPolystyrene nanoparticles promote endometrial cancer development through the ACSS2-mediated reprogramming of arachidonic acid metabolism

Microplastics and nanoplastics are commonly found in our everyday environments. So far, microplastics and nanoplastics have been detected in various tissues and bodily fluids, including hair, sputum, digestive tissue, lungs, blood, and placental tissue. Although some studies indicate that micropl...

2026-02-05 | MTBLS13850 | MetaboLights
MetabolomicsZinc oxide nanoparticles supplementation improve the quality and lipid profiles of boar frozen semen

Oxidative stress frequently causes a reduction in the quality of frozen-thawed sperm. Zinc oxide nanoparticles (ZnONPs) has an antioxidant protective effect on frozen semen of animals such as goats, camels and buffaloes. However, it is not clear whether ZnONPs can improve the quality and lipid co...

2026-05-05 | MTBLS12892 | MetaboLights
MetabolomicsQuantitative multi-Omics analysis of paclitaxel-loaded Poly(lactide-co-glycolide) nanoparticles for identification of potential biomarkers for head and neck cancer
Not available
ORGANISM(S): Homo sapiens 
ST002248 | MetabolomicsWorkbench
TranscriptomicsDNA methylation profiling of BEAS-2B cells exposed to low doses of Ag nanoparticles for 6 weeks
Human bronchial lung cells (BEAS-2B) were treated for 6 weeks with low doses (1 µg/mL) of Ag nanoparticles (10 nm citrate-coated). At the end of the exposure control and treated samples were submitted for DNA methylation analysis (Illumina 450k). The overall goal of this experiment was to evaluate p...
ORGANISM(S): Homo sapiens 
2018-04-30 | E-MTAB-6331 | biostudies-arrayexpress
TranscriptomicsRNA-Seq of BEAS-2B cells treated with low doses of Ag nanoparticles for 6 weeks
Human bronchial lung cells (BEAS-2B) were treated for 6 weeks with low doses (1 µg/mL) of Ag nanoparticles (10 nm citrate coated). At the end of the exposure control and treated samples were submitted for RNA-Seq analysis (Hiseq2500). The overall goal of this experiment was to gain an in-depth under...
ORGANISM(S): Homo sapiens 
2018-04-30 | E-MTAB-6321 | biostudies-arrayexpress
TranscriptomicsThe effect of CuO nanoparticles on gene expression patterns in Daphnia magna
There is still a lot of contradiction on whether metal ions are solely responsible for the observed the toxicity of ZnO and CuO nanoparticles to aquatic species. While most tests have studied nanoparticle effects at organismal levels (e.g. mortality, reproduction), effects at suborganismal levels ma...
ORGANISM(S): Daphnia magna 
2014-03-01 | E-GEOD-54738 | biostudies-arrayexpress
TranscriptomicsThe effect of ZnO nanoparticles on gene expression patterns in Daphnia magna
There is still a lot of contradiction on whether metal ions are solely responsible for the observed the toxicity of ZnO and CuO nanoparticles to aquatic species. While most tests have studied nanoparticle effects at organismal levels (e.g. mortality, reproduction), effects at suborganismal levels ma...
ORGANISM(S): Daphnia magna 
2014-03-01 | E-GEOD-54736 | biostudies-arrayexpress
TranscriptomicsRNA-Seq of BEAS-2B cells treated with low doses of Ni and NiO nanoparticles as well as NiCl2 for 6 weeks
Human bronchial lung cells (BEAS-2B) were treated for 6 weeks with low doses (0.5 µg/mL) of Ni and NiO nanoparticles and NiCl2. At the end of the exposure control and treated samples were submitted for RNA-Seq analysis (Hiseq2500). The overall goal of this experiment was to gain an in-depth understa...
ORGANISM(S): Homo sapiens 
2020-04-19 | E-MTAB-8903 | biostudies-arrayexpress
TranscriptomicsSilica nanoparticles effects on gene expression of A549 cells
Expansion of nanotechnology will bring many potential benefits as adversely effects on human health. Protection of the human respiratory system from exposure of volatile nanoparticles has become an emerging health concern. The understanding of the biological processes involved in the development and...
ORGANISM(S): Homo sapiens 
2014-09-08 | E-GEOD-53700 | biostudies-arrayexpress
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