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GenomicsMicroarray transcriptomic data from LNCaP cells treated with vehicle, 10 nM bufalin or 20 nM bufalin for 24 h
Microarray transcriptomic data from LNCaP cells treated with vehicle, 10 nM bufalin or 20 nM bufalin for 24 h
PRJNA485639 | ENA
TranscriptomicsMicroarray transcriptomic data from LNCaP cells treated with vehicle, 10 nM bufalin or 20 nM bufalin for 24 h
Bufalin is a major cardiotonic compound in the traditional Chinese medicine Chanshu preparations of toad skin secretions. Cell culture studies have suggested anti-cancer potential involving multiple cellular processes including differentiation, apoptosis, senescence and angiogenesis. In prostate can...
ORGANISM(S): Homo sapiens 
2018-08-13 | GSE118261 | GEO
TranscriptomicsGenomic Analysis of effect of bufalin on HL60 Cells
Bufalin, a natural toxin isolated from the Chinese toad venom preparation Chan ’su, has been used in leukemia therapy in the mainland China by inducing human leukemia cells to differentiation and apoptosis. In the present study, oligonucleotide microarrays were used to assess profiles of target gene...
ORGANISM(S): Homo sapiens 
2006-11-29 | GSE6347 | GEO
ProteomicsGlobal Metabolomic and Lipidomic Analysis Reveal the Synergistic Effect of Bufalin in Combination with Cinobufagin against HepG2 Cells
Chansu, which is prepared from the skin secretions of toad (Bufo bufo gargarizans Cantor), is widely used in traditional Chinese medicine (TCM). Being the principal bioactive constituents of ChanSu, bufalin (BFL) and cinobufagin (CBF) have been shown to possess anticancer properties. TCM confer bioa...
ORGANISM(S): Homo sapiens (Human) 
2020-01-20 | PXD016926 | Pride
Metabolomics Bufalin Combination treatment. Lipidomics Cinobufagin 
GenomicsThe mechanism of cardiotoxicity induced by piperlopicin and bufalin was revealed by epitranscriptomics
The mechanism of cardiotoxicity induced by piperlopicin and bufalin was revealed by epitranscriptomics
PRJNA1131336 | ENA
GenomicsTargeting p160 SRCs in prostate cancer with bufalin (1)
Targeting p160 SRCs in prostate cancer with bufalin (1)
PRJNA613262 | ENA
GenomicsTargeting p160 SRCs in prostate cancer with bufalin (2)
Targeting p160 SRCs in prostate cancer with bufalin (2)
PRJNA613448 | ENA
OtherThe mechanism of cardiotoxicity induced by piperlopicin and bufalin was revealed by epitranscriptomics
By using epitranscriptomics, the mechanism of cardiotoxicity induced by piperlopicin and bufalin was discovered and confirmed through fluorescence imaging, RT-qPCR, and Western blotting. Experimental findings indicated that piperlopicin and bufalin altered m6A levels within the cells.
ORGANISM(S): Rattus norvegicus 
2026-07-31 | GSE271405 | GEO
UnknownSynthesis and Biological Evaluation of Novel Bufalin Derivatives.
Not available
S-EPMC8999407 | biostudies-literature
UnknownBufalin suppresses ovarian cancer cell proliferation via EGFR pathway.
Not available
S-EPMC8869555 | biostudies-literature
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