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ProteomicsVaginal epithelial dysfunction is mediated by the microbiome, metabolome, and mTOR signaling - Participant Group 1
Bacterial vaginosis (BV) is characterized by depletion of Lactobacillus and overgrowth of anaerobic and facultative bacteria, leading to increased mucosal inflammation, epithelial disruption, and poor reproductive health outcomes. However, the molecular mediators contributing to vaginal epithelial ...
ORGANISM(S): Homo sapiens (Human) 
2023-07-20 | PXD040895 | Pride
Human Lc-msms Bacterial vaginosis Microbiome Proteome 
ProteomicsVaginal epithelial dysfunction is mediated by the microbiome, metabolome, and mTOR signaling - Participant Group 2
Bacterial vaginosis (BV) is characterized by depletion of Lactobacillus and overgrowth of anaerobic and facultative bacteria, leading to increased mucosal inflammation, epithelial disruption, and poor reproductive health outcomes. However, the molecular mediators contributing to vaginal epithelial ...
ORGANISM(S): Homo sapiens (Human) 
2023-07-20 | PXD040280 | Pride
Human Lc-msms Bacterial vaginosis Microbiome Proteome 
ProteomicsGenital proteins in women at risk of HIV infection
In this study, we used a bead-based affinity proteomics method to examine genital proteins in women living in HIV-serodiscordant relationships. Proteins identified using the affinity set-up were validated by a label free tandem mass spectrometry based method in a parallel cohort with concordant resu...
ORGANISM(S): Homo sapiens (Human) 
2018-12-10 | PXD009723 | Pride
Cervicovaginal secretions 
TranscriptomicsSystems Biology Analysis of Tenofovir 1% Gel in a Phase I Rectal Microbicide Trial
In MTN-007, a phase 1, randomized, double-blinded rectal microbicide trial, we used systems genomics/proteomics to determine the effect of tenofovir 1% gel, nonoxynol-9 2% gel, placebo gel or no treatment on rectal biopsies taken at baseline, after one application or after seven daily applications (...
ORGANISM(S): Homo sapiens 
2015-02-23 | E-GEOD-57025 | biostudies-arrayexpress
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