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MetabolomicsOn-line untargeted metabolomics monitoring of an Escherichia coli succinate fermentation process
The real-time monitoring of metabolites (RTMet) is instrumental for the industrial production of biobased fermentation products. This study shows the first application of untargeted on-line metabolomics for the monitoring of undiluted fermentation broth samples taken automatically from a 5 L bioreac...
2023-04-26 | MTBLS5197 | MetaboLights
ProteomicsGlobal phosphoproteomic mapping of early mitotic exit in human cells identifies novel substrate dephosphorylation motifs
Entry into mitosis is driven by the coordinated phosphorylation of thousands of proteins. For the cell to complete mitosis and divide into two identical daughter cells it must regulate dephosphorylation of these proteins in a highly ordered, temporal manner. There is currently a lack of a complete u...
ORGANISM(S): Homo sapiens (Human) 
2015-06-25 | PXD001559 | Pride
Motif Spindle assembly checkpoint. Mitosis Phosphatase Silac Prc1 Myc Phosphorylation Mitotic exit Kinase Phosphoproteomics 
UnknownEnsa controls S-phase length by modulating Treslin levels.
Not available
S-EPMC5547116 | biostudies-literature
MetabolomicsStreamlined identification of strain engineering targets for bioprocess improvement using metabolic pathway enrichment analysis
Metabolomics is a powerful tool for the identification of genetic targets for bioprocess optimisation. However, in most cases, only the biosynthetic pathway directed to product formation is analysed, limiting the identification of these targets. Some studies have used untargeted metabolomics, allowi...
2023-08-31 | MTBLS6667 | MetaboLights
UnknownA new Burgess Shale-type deposit from the Ediacaran of western Mongolia.
Not available
S-EPMC4796905 | biostudies-literature
MetabolomicsNovel Minor Groove Binders cure animal African trypanosomiasis in an in vivo mouse model
Animal African trypanosomiasis (AAT) is a significant socioeconomic burden for sub-Saharan Africa because of its huge impact on livestock health. Existing therapies including those based on minor groove binders (MGBs), such as the diamidines, which have been used for decades, have now lost efficacy ...
2022-01-18 | MTBLS882 | MetaboLights
MetabolomicsA novel targeted/untargeted GC-Orbitrap metabolomics methodology applied to Candida albicans and Staphylococcus aureus biofilms

INTRODUCTION: Combined infections from Candida albicans and Staphylococcus aureus are a leading cause of death in the developed world. Evidence suggests that Candida enhances the virulence of Staphylococcus - hyphae penetrate through tissue bar...

2017-02-20 | MTBLS370 | MetaboLights
UnknownFunctionalization of the 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene (BODIPY) core.
Not available
S-EPMC2430868 | biostudies-literature
UnknownThiopurine S-methyltransferase pharmacogenetics: autophagy as a mechanism for variant allozyme degradation.
Not available
S-EPMC2583164 | biostudies-literature
TranscriptomicsWhy nicotine is BAD for your Fallopian tube: an explanation for the association between smoking and ectopic pregnancy
Why nicotine is BAD for your Fallopian tube: an explanation for the association between smoking and ectopic pregnancy
ORGANISM(S): Homo sapiens 
2014-08-01 | E-MTAB-1290 | biostudies-arrayexpress
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