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TranscriptomicsTestis-to-ovary reprogramming and testis regression after ablation of Sox9 in Sox8-/- mice
We used two Sertoli-cell-specific Cre lines: Wt1-CreERT2 and Sox9-CreERT2, to induce Sox9 ablation on a Sox8 -/- background in the adult testis. Sox9/8 double KO testes undergo testis-to-ovary genetic reprogramming and Sertoli-to-granulosa cell transdifferentiation.
ORGANISM(S): Mus musculus 
2016-06-08 | E-MTAB-4572 | biostudies-arrayexpress
UnknownSARS-CoV-2 adaptive immunity in nursing home residents up to eight months after two doses of the Comirnaty® COVID-19 vaccine.
Not available
S-EPMC8889892 | biostudies-literature
TranscriptomicsEffects on adult testis of Sertoli cell-specific ablation of miR-17-92 in mouse embryos
We induced specific deletion of miR-17-92 in Sertoli cells at the time of Amh expression in mouse embryos. We analyzed the effect of this deletion in the long term in adult testis. The transcriptome of mutant testis was consistently altered but do not produce a phenotype due to the testis homeostasi...
ORGANISM(S): Mus musculus 
2018-05-10 | E-MTAB-5914 | biostudies-arrayexpress
TranscriptomicsTranscriptome comparison of active and regressed testes of Microtus duodecimcostatus
We also study the changes occurring in the testes of Mediterranean pine mice living in the wastelands during the breeding cycle. The transcriptomic analysis of active and regressed testis show that several molecular pathways that operate in Sertoli cells, involved in the control of spermatogenesis a...
ORGANISM(S): Microtus duodecimcostatus 
2021-08-02 | E-MTAB-10291 | biostudies-arrayexpress
TranscriptomicsMicroRNA profiling of mouse embryo gonad during the critical period of sex determination
Expression profiling of micro RNAs in mouse embryonic gonads before (11.5 days post coitum) and after (13.5 days post coitum) the critical period of sex determination
ORGANISM(S): Mus musculus 
2012-05-11 | E-MEXP-2252 | biostudies-arrayexpress
TranscriptomicsEffect of miR-106b~25 in mouse spermatogenesis and male fertility
We investigated the miRNA cluster miR-106b~25 as potential candidate causing male infertility. We analized single and double KO mice. Single KO show derregulation of multiple molecular pathways and disrupted early spermatogenesys, but retain fertility. Double KO show severely disrupted testicular hi...
ORGANISM(S): Mus musculus 
2020-11-06 | E-MTAB-8964 | biostudies-arrayexpress
UnknownHigh-Performance Aramids with Intrinsic Bactericide Activity.
Not available
S-EPMC10895584 | biostudies-literature
UnknownThe Mediating Role of the Self-Concept Between the Relationship of the Body Satisfaction and the Intention to Be Physically Active in Primary School Students.
Not available
S-EPMC7225284 | biostudies-literature
UnknownCombined creatine and β-hydroxy-β-methylbutyrate supplementation with integral conditioning exercise enhances functional performance and metabolic health in physically active older adults: A randomized controlled crossover trial.
Not available
S-EPMC12819432 | biostudies-literature
UnknownAssociation Between Insulin-Like Growth Factor-1 and Social Cognition in Huntington's Disease.
Not available
S-EPMC9941927 | biostudies-literature
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