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TranscriptomicsTranscription profiling of Burkholderia pseudomallei under salt stress and the effect on a type III secretion system
Effect of NaCl of gene expression in Burkholderia pseudomallei at two time points
ORGANISM(S): Burkholderia pseudomallei 
2010-06-03 | E-MEXP-2302 | biostudies-arrayexpress
TranscriptomicsGenomic Loss of Penicillin-Binding Protein 3 in Burkholderia pseudomallei Confers Clinical Resistance to Ceftazidime
Array-CGH analysis and Burkholderia pseudomallei isolates pre and post ceftazidime relapse. Genomic DNA from both the parental strains and variant strains were labeled with Cy3 or Cy5 fluorescent dyes and hybridized onto a customized microarray with probes designed from the reference Bp K96243 genom...
ORGANISM(S): Burkholderia pseudomallei 
2011-10-06 | E-GEOD-25832 | biostudies-arrayexpress
ProteomicsRole of ppiB in burkholderia pseudomallei
Burkholderia pseudomallei is the causative agent of melioidosis a disease endemic in South-East Asia and Northern Australia. The mortality rates in these areas are unacceptably high even with antibiotic treatment, attributed to intrinsic and acquired resistance of B. pseudomallei to antibiotics. Wi...
ORGANISM(S): Burkholderia pseudomallei 
2019-08-05 | PXD012956 | Pride
Burkholderia pseudomallei Lfq Proteomics 
TranscriptomicsInfection with Burkholderia pseudomallei – immune correlates of survival in acute melioidosis
Melioidosis is a neglected tropical disease caused by the Gram-negative bacterium Burkholderia pseudomallei. It is widespread in Southeast Asia and under-reported across tropical regions worldwide. Patients present with a range of clinical syndromes including sepsis, pneumonia and focal abscesses, w...
ORGANISM(S): Homo sapiens 
2017-09-22 | E-MTAB-6093 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of diabetic vs non-diabetic human blood cells infected with Burkholderia pseudomallei
To gain insight into the role of glibenclamide treatment of diabetic patients in melioidosis (Burkholderia pseudomaleii infection)
ORGANISM(S): Homo sapiens 
2010-12-31 | E-TABM-852 | biostudies-arrayexpress
TranscriptomicsComparative transcriptomics of Burkholderia pseudomallei from soil media and infected host
Burkholderia pseudomallei can adapt to and thrive in a variety of environments, including soil and water, and also can infect different hosts, including humans, leading to the tropical disease melioidosis. Modulation of gene and protein expression is one of this pathogen's adaptive survival mechanis...
ORGANISM(S): Burkholderia pseudomallei 
2022-07-22 | E-MTAB-11200 | biostudies-arrayexpress
ProteomicsThe expression of virulence and antimicrobial related proteins in different Burkholderia mallei and Burkholderia pseudomallei isolates
Burkholderia mallei and Burkholderia pseudomallei are both potential biological threats agents. Melioidosis caused by B. pseudomallei is endemic in Southeast Asia and Northern Australia, while glanders caused by B. mallei infections are rare. Here we studied the proteomes of different B. mallei and ...
ORGANISM(S): Burkholderia mallei Burkholderia pseudomallei 
2022-12-15 | PXD028126 | Pride
Burkholderia mallei burkholderia pseudomallei proteome lc-ms/ms colony 
TranscriptomicsGenome-wide analysis of blood, spleen and lung expression of C57BL/6 mice subjected to Burkholderia pseudomallei infection
Melioidosis, a severe human disease caused by the bacterium Burkholderia pseudomallei, has a wide spectrum of clinical manifestations ranging from acute septicaemia to chronic localized illness or latent infection. Mice were intranasally infected with either high or low doses of B. pseudomallei to g...
ORGANISM(S): Mus musculus 
2015-09-02 | E-GEOD-61106 | biostudies-arrayexpress
ProteomicsQuantitative proteomic analysis of Burkholderia pseudomallei Bsa Type III secretion system effectors using hyper-secreting mutants
Burkholderia pseudomallei is an intracellular pathogen and the causative agent of melioidosis, a severe disease of humans and animals. One of the virulence factors critical for early stages of infection is the Burkholderia secretion apparatus (Bsa) Type 3 Secretion System (T3SS), a molecular syringe...
ORGANISM(S): Burkholderia pseudomallei (strain K96243) 
2015-01-28 | PXD001656 | Pride
Effector T3ss Type iii secretion system Burkholderia pseudomallei Melioidosis Itraq 
TranscriptomicsComparative genomic analysis of 93 Bp strains using K96243 as the reference
Natural isolates of Burkholderia pseudomallei (Bp), the causative agent of melioidosis, are known to exhibit diverse phenotypic traits, suggesting significant intraspecies genetic heterogeneity. Using whole-genome Bp microarrays, we experimentally mapped patterns of large-scale genomic variation in ...
ORGANISM(S): Burkholderia pseudomallei K96243 
2008-12-25 | E-GEOD-9491 | biostudies-arrayexpress
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