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Melioidosis is a neglected tropical disease caused by the Gram-negative bacterium Burkholderia pseudomallei. It is widespread in Southeast Asia and under-reported across tropical regions worldwide. Patients present with a range of clinical syndromes including sepsis, pneumonia and focal abscesses, w...
ORGANISM(S): Homo sapiens 
Whole blood transcriptomics of patients with melioidosis
Whole blood transcriptomics of patients with melioidosis
The purpose of this study was to develop a comprehensive picture of the host transcriptional response during the acute stage of melioidosis. To adress this, we compared the transcriptome of infected liver and spleen with uninfected tissues over an infection period of 42 hr (16 hpi, 24 hpi and 42 hpi...
ORGANISM(S): Mus musculus 
To gain insight into the role of glibenclamide treatment of diabetic patients in melioidosis (Burkholderia pseudomaleii infection)
ORGANISM(S): Homo sapiens 
Burkholderia pseudomallei strain:BPs122 | isolate:Melioidosis patient Genome sequencing
Burkholderia pseudomallei strain:BPs115 | isolate:Melioidosis patient Genome sequencing
Burkholderia pseudomallei strain:BPs116 | isolate:Melioidosis patient Genome sequencing
Burkholderia pseudomallei strain:BPs111 | isolate:Melioidosis patient Genome sequencing
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