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TranscriptomicsImmediate/Early Response to Trypanosoma cruzi Infection Involves Minimal Modulation of Host Cell Transcription
Host cell infection by the intracellular pathogen, Trypanosoma cruzi, involves activation of signaling pathways, cytoskeletal reorganization, and targeted recruitment of host cell lysosomes. To determine the consequences of T. cruzi invasion on host cell gene expression, high density microarrays con...
ORGANISM(S): Homo sapiens 
2005-10-20 | E-GEOD-3476 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of T. cruzi infection : 24 hours
Host cell infection by the intracellular pathogen, Trypanosoma cruzi, involves activation of signaling pathways, cytoskeletal reorganization, and targeted recruitment of host cell lysosomes. To determine the consequences of T. cruzi invasion on host cell gene expression, high density microarrays con...
ORGANISM(S): Homo sapiens 
2005-09-26 | E-SMDB-1560 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of T. cruzi : parasite-conditioned medium
Host cell infection by the intracellular pathogen, Trypanosoma cruzi, involves activation of signaling pathways, cytoskeletal reorganization, and targeted recruitment of host cell lysosomes. To determine the consequences of T. cruzi invasion on host cell gene expression, high density microarrays con...
ORGANISM(S): Homo sapiens 
2005-09-26 | E-SMDB-1563 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of T. cruzi, parasite control RNA
Host cell infection by the intracellular pathogen, Trypanosoma cruzi, involves activation of signaling pathways, cytoskeletal reorganization, and targeted recruitment of host cell lysosomes. To determine the consequences of T. cruzi invasion on host cell gene expression, high density microarrays con...
ORGANISM(S): Homo sapiens 
2005-09-26 | E-SMDB-1561 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of T. cruzi : 2-6 hours infection
Host cell infection by the intracellular pathogen, Trypanosoma cruzi, involves activation of signaling pathways, cytoskeletal reorganization, and targeted recruitment of host cell lysosomes. To determine the consequences of T. cruzi invasion on host cell gene expression, high density microarrays con...
ORGANISM(S): Homo sapiens 
2005-09-26 | E-SMDB-1562 | biostudies-arrayexpress
TranscriptomicsExpression data from human primary fibroblasts treated with Trypanosoma cruzi-conditioned medium
The intracellular pathogen Trypanosoma cruzi secretes an activity that blocks TGF-β-dependent induction of connective tissue growth factor (CTGF/CCN2). Here, we address the mechanistic basis for T. cruzi-mediated interference of CTGF/CCN2 expression by examining host cell signaling pathways and the...
ORGANISM(S): Homo sapiens 
2011-09-08 | E-GEOD-16416 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse skin 24 hours after intradermal infection with Trypanosoma cruzi
To investigate the early host response triggered by three different strains of Trypanosoma cruzi at a local infection site, changes in host gene expression were monitored in a murine intradermal infection model using Affymetrix oligonucleotide arrays. Robust induction of IFN-stimulated genes (ISGs) ...
ORGANISM(S): Mus musculus 
2009-01-14 | E-GEOD-13522 | biostudies-arrayexpress
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