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TranscriptomicsBoolean modeling reveals the necessity of transcriptional regulation for bistablity in PC12 Cell Differentiation
The nerve growth factor NGF has been shown to cause cell fate decisions towards either differentiation or proliferation depending on the relative activity of downstream pERK, pAKT or pJNK signaling. However, how these protein signals are translated into and fed back from transcriptional activity to ...
ORGANISM(S): Rattus norvegicus 
2016-03-23 | E-GEOD-74327 | biostudies-arrayexpress
TranscriptomicsModeling the time resolved transcriptional signature of time sequential stimulation with HGF and IL-6 in hepatocyte proliferation
Liver regeneration is characterized by a scheduled sequence of inner and intra-cellular signaling events. It starts with an initial inflammatory phase, followed by a period of rapidly proliferating hepatocytes and stopping abruptly when the liver mass is restored. The cytokines hepatocellular growth...
ORGANISM(S): Mus musculus 
2016-06-01 | E-GEOD-69935 | biostudies-arrayexpress
TranscriptomicsExpression data from mitochondrial protease ClpP knock-out mice.
The peptidase ClpP is conserved from bacteria to human. In the mitochondrial matrix, it multimerizes and forms a macromolecular proteasome-like cylinder. Because of its known relevance for the mitochondrial unfolded protein response during cell stress, we characterized two ClpP knock-out mouse found...
ORGANISM(S): Mus musculus 
2013-07-17 | E-GEOD-40207 | biostudies-arrayexpress
TranscriptomicsSystematic analysis of time resolved transcriptional signature of the cross-talk between HGF and IL-6 refines the role of Cxcl10 in hepatocyte proliferation control
Liver regeneration is characterized by a scheduled sequence of inner and intra-cellular signaling events. It starts with an initial inflammatory phase, followed by a period of rapidly proliferating hepatocytes and stopping abruptly when the liver mass is restored. The cytokines hepatocellular growth...
ORGANISM(S): Mus musculus 
2016-06-01 | E-GEOD-69928 | biostudies-arrayexpress
UnknownEnoxaparin for primary thromboprophylaxis in symptomatic outpatients with COVID-19 (OVID): a randomised, open-label, parallel-group, multicentre, phase 3 trial.
Not available
S-EPMC9243568 | biostudies-literature
UnknownLong-term course of ambulatory patients with COVID-19 initially treated with enoxaparin vs no anticoagulation: final analysis of the OVID (enoxaparin for outpatients with COVID-19) randomized trial.
Not available
S-EPMC11381852 | biostudies-literature
UnknownEvolutionary trajectories of small cell lung cancer under therapy.
Not available
S-EPMC10972747 | biostudies-literature
UnknownObservation of quantum entanglement with top quarks at the ATLAS detector.
Not available
S-EPMC11410654 | biostudies-literature
UnknownGlobal, regional, and national prevalence of adult overweight and obesity, 1990-2021, with forecasts to 2050: a forecasting study for the Global Burden of Disease Study 2021.
Not available
S-EPMC11920007 | biostudies-literature
UnknownEfficacy and Safety of Degludec versus Glargine in Type 2 Diabetes.
Not available
S-EPMC5731244 | biostudies-literature
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