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MetabolomicsRed-Fleshed Apple Anthocyanin Extracts Attenuate Male Reproductive System Dysfunction Caused by Busulfan in Mice (Mouse blood plasma; UPLC-MS/MS assays)

In this research, we analyzed the effect of oral administration of red-fleshed apple anthocyanin extract (RAAE) on busulfan-treated mice. At first, we showed that the most abundant component in RAAE was cyanidin 3-O-galactoside. To determine the effect of RAAE, mice were divided into control and ...

2021-06-07 | MTBLS2782 | MetaboLights
MetabolomicsRed-Fleshed Apple Anthocyanin Extracts Attenuate Male Reproductive System Dysfunction Caused by Busulfan in Mice (Apple extract; UPLC-MS/MS assay)

In this research, we analyzed the effect of oral administration of red-fleshed apple anthocyanin extract (RAAE) on busulfan-treated mice. At first, we showed that the most abundant component in RAAE was cyanidin 3-O-galactoside. To determine the effect of RAAE, mice were divided into control and ...

2021-06-07 | MTBLS2863 | MetaboLights
ProteomicsLabel-free quantification of busulfan-treated testis
The busulfan-treated mouse model showed abnormal testis morphology and reduced sperm number and testis weight. Testicular and sperm damage was most severe at 30 days after busulfan treatment. The protein level of MGAT1 was increased in busulfan-treated mouse testis. The busulfan-treated mouse testes...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-06 | PXD035492 | Pride
Testis Busulfan Label-free quantification Spermatogenesis 
TranscriptomicsGene expression profiles of Lhcgr-deficient testes
Spermatogonial stem cells (SSCs) provide foundation for spermatogenesis by undergoing continuous self-renewal division. Previous studies have reported conflicting results on the role of the pituitary gland activity in SSC self-renewal. In this study, we analyzed the role of hormonal regulation of SS...
ORGANISM(S): Mus musculus 
2016-07-15 | E-GEOD-77500 | biostudies-arrayexpress
GenomicsL.J. could rescure the adverse effects induced by busulfan on the testis
L.J. could rescure the adverse effects induced by busulfan on the testis
PRJNA766423 | ENA
GenomicsL.J. could rescure the adverse effects induced by busulfan on the spleen
L.J. could rescure the adverse effects induced by busulfan on the spleen
PRJNA766422 | ENA
GenomicsL.J. could rescure the adverse effects induced by busulfan on the kidney
L.J. could rescure the adverse effects induced by busulfan on the kidney
PRJNA766419 | ENA
GenomicsL.J. could rescure the adverse effects induced by busulfan on the liver
L.J. could rescure the adverse effects induced by busulfan on the liver
PRJNA766420 | ENA
GenomicsRNA sequencing analysis of busulfan-treated initial segment-caput epididymis.
RNA sequencing analysis of busulfan-treated initial segment-caput epididymis.
PRJNA1040783 | ENA
TranscriptomicsBulk RNA-seq for undifferentiated spermatogonia from the testes of control, aged and busulfan-treated C57BL/6 mice
Samples were prepared from 100 GFRa1-GFP positive, Miwi2-tdTom negative and 100 GFRa1-GFP negative, Miwi2-tdTom positive cells that were sorted with FACS. cDNA libraries were prepared with the SMARTseq2 protocol. Adult, control samples had four biological replicates while the aged and busulfan-trea...
ORGANISM(S): Mus musculus 
2022-02-28 | E-MTAB-9238 | biostudies-arrayexpress
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