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TranscriptomicsVisceral Endoderm differentiation mediated by Hnf1B and is required for epiblast survival
E5.0 entails an intermediate state for primitive endoderm (PE) to visceral endoderm (VE) differentiation: a process required for proper embryonic development. Hnf1b is essential for primitive to visceral endoderm differentiation from E4.5 to E5.5. To understand development at E5.0 and pinpoint the r...
ORGANISM(S): Mus musculus 
2024-11-19 | E-MTAB-11140 | biostudies-arrayexpress
TranscriptomicsIsolation and functional characterization of the arteriole hematopoietic stem cell niche
Hematopoietic stem cells (HSCs) inhabit distinct microenvironments within the adult bone marrow (BM) that govern the delicate balance between HSC quiescence, self-renewal, and differentiation. It has been suggested that quiescent HSCs localize adjacent to BM arteriole endothelial cells in a signific...
ORGANISM(S): Mus musculus 
2015-11-04 | E-GEOD-61636 | biostudies-arrayexpress
TranscriptomicsLongitudinal scRNAseq profiling of memory B cells in mRNA vaccinated individuals post BA.1-breakthrough infection
Memory B cells play a fundamental role in host defenses against viruses. This dataset aimed at understanding the recruitment and remodeling of the memory B cell repertoire in the context of BA.1-breakthrough infection in BNT162b2 mRNA vaccinated individuals. All four donors enrolled in the study had...
ORGANISM(S): Homo sapiens 
2023-08-15 | E-MTAB-12651 | biostudies-arrayexpress
UnknownAn Intervention to Improve Physical Function and Caregiver Perceptions in Family Caregivers of Persons With Heart Failure.
Not available
S-EPMC6026574 | biostudies-literature
UnknownArgon plasma surface modification promotes the therapeutic angiogenesis and tissue formation of tissue-engineered scaffolds in vivo by adipose-derived stem cells.
Not available
S-EPMC6440049 | biostudies-literature
UnknownAdipose derived stem cells and platelet rich plasma improve the tissue integration and angiogenesis of biodegradable scaffolds for soft tissue regeneration.
Not available
S-EPMC7688190 | biostudies-literature
TranscriptomicsTranscription profiling of G sulfurreducens GGS Fe(III) vs fumarate
G. sulfurreducens (ATCC #51573) was obtained from the laboratory culture collection of Dr. Derek Lovley. Cells were grown under strict anaerobic conditions at 30 °C in chemostats, (see Esteve-Núñez, A., M. M. Rothermich, M. Sharma, and D. R. Lovley. 2004. Growth of Geobacter sulfurreducens under nut...
ORGANISM(S): Geobacter sulfurreducens 
2005-01-01 | E-TIGR-81 | biostudies-arrayexpress
TranscriptomicsNANOG alone induces germ cells in primed epiblast in vitro by activation of enhancers
Nanog, a core pluripotency factor in the inner cell mass of blastocysts, is also expressed in unipotent primordial germ cells (PGC) in mice1, where its precise role is yet unclear2-4. We investigated this in an in vitro model, where naïve pluripotent embryonic stem cells (ESCs) cultured in bFGF/Act...
ORGANISM(S): Mus musculus 
2016-01-11 | E-GEOD-71933 | biostudies-arrayexpress
UnknownCancer Risks in Patients Treated With Growth Hormone in Childhood: The SAGhE European Cohort Study.
Not available
S-EPMC6061931 | biostudies-literature
TranscriptomicsEmbedding siRNA sequences targeting Apolipoprotein B100 in shRNA and miRNA scaffolds results in differential processing and in vivo efficacy
Purpose: Identical predicted small interfering RNA (siRNA) sequences targeting Apolipoprotein B100 (siApoB) were embedded in shRNA (shApoB) or miRNA (miApoB) scaffolds and a direct compariso of the possible aspecific off-target effects in vivo was performed. Next generation sequencing (NGS) of smal...
ORGANISM(S): Homo sapiens 
2012-07-10 | E-GEOD-39187 | biostudies-arrayexpress
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