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TranscriptomicsButyrophilin 3A1 binds phosphorylated antigens and stimulates human TCR γδ cells.
We used genetic approaches to identify butyrophilin 3A1 (BTN3A1) as the molecule that binds and presents phosphorylated antigens to Vγ9Vδ2 TCR–expressing cells. BTN3A1 represents a novel antigen–presenting molecule for the activation of Vγ9Vδ2 TCR–expressing cells which play important roles in human...
ORGANISM(S): Homo sapiens 
2012-10-01 | GSE37634 | GEO
TranscriptomicsButyrophilin 3A1 binds phosphorylated antigens and stimulates human TCR M-NM-3M-NM-4 cells.
We used genetic approaches to identify butyrophilin 3A1 (BTN3A1) as the molecule that binds and presents phosphorylated antigens to VM-NM-39VM-NM-42 TCRM-bM-^@M-^Sexpressing cells. BTN3A1 represents a novel antigenM-bM-^@M-^Spresenting molecule for the activation of VM-NM-39VM-NM-42 TCRM-bM-^@M-^Sex...
ORGANISM(S): Homo sapiens 
2012-10-01 | E-GEOD-37634 | biostudies-arrayexpress
ProteomicsButyrophilin 3A1 contributes to inflammation and induces a lupus-like disease by inhibiting the IL-38-ferroptosis axis
Regarding proteomics, spleen tissue was milled on ice and tissue was lysed using RIPA lysis solution. Lysis was further assisted by treatment of ultrasound. Samples of protein solution were obtained by centrifugation. Then, the samples were proteolytically digested, and evaluated by DIA mass spectro...
ORGANISM(S): Mus musculus (Mouse) 
2025-09-22 | PXD064490 | Pride
Butyrophilin 3a1 Lupus Inflammation Il-38 
UnknownThe butyrophilin 3A1 intracellular domain undergoes a conformational change involving the juxtamembrane region.
Not available
S-EPMC5636706 | biostudies-literature
UnknownThe intracellular B30.2 domain of butyrophilin 3A1 binds phosphoantigens to mediate activation of human Vγ9Vδ2 T cells.
Not available
S-EPMC4028361 | biostudies-literature
UnknownSensor Function for Butyrophilin 3A1 in Prenyl Pyrophosphate Stimulation of Human Vγ2Vδ2 T Cells.
Not available
S-EPMC4848273 | biostudies-literature
GenomicsHomo sapiens
Butyrophilin 3A1 binds phosphorylated antigens and stimulates human TCR γδ cells.
PRJNA162417 | ENA
UnknownPhosphoantigen-induced conformational change of butyrophilin 3A1 (BTN3A1) and its implication on Vγ9Vδ2 T cell activation.
Not available
S-EPMC5584448 | biostudies-literature
UnknownButyrophilin 3A1 Contributes to Inflammation and Induces a Lupus-Like Disease by Inhibiting the IL-38-Ferroptosis Axis.
Not available
S-EPMC12433891 | biostudies-literature
UnknownPhosphoantigens glue butyrophilin 3A1 and 2A1 to activate Vγ9Vδ2 T cells.
Not available
S-EPMC10533412 | biostudies-literature
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