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Interleukin (IL)-1 family cytokines are essential for host defense at epithelial barriers. The IL-1 family member IL-33 was recently linked to stress granules (SGs). Formation of SGs and other biomolecular condensates is promoted by proteins containing low complexity regions (LCRs). Computational an...
ORGANISM(S): Homo sapiens (Human) 
2024-11-03 | PXD052918 | Pride
Gene expression signature in ablated IL-38 PyMT tumors dependent on 훾훿 T cells
Regarding proteomics, spleen tissue was milled on ice and tissue was lysed using RIPA lysis solution. Lysis was further assisted by treatment of ultrasound. Samples of protein solution were obtained by centrifugation. Then, the samples were proteolytically digested, and evaluated by DIA mass spectro...
ORGANISM(S): Mus musculus (Mouse) 
2025-09-22 | PXD064490 | Pride
We studied the impact of IL-38 neutralization on tumor immune control in PyMT mammary carcinoma mouse model via γδ T cells. To that end, whole transcriptome profile of PyMT tumors upon in vivo IL-38 neutralization and γδ-TCR blockage were generate via next generation mRNA sequencing on a NextSeq 200...
ORGANISM(S): Mus musculus 
2024-08-16 | GSE239398 | GEO
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