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A study of a marked QTL affecting body weight segregating in an inter-cross of a broiler and layer chickens. QTL genotypes were inferred on flanking markers and RNA from breast tissue of birds with alternative QTL genotypes was hybridized onto microarrays
ORGANISM(S): Gallus gallus 
The Polycomb group gene BMI1 is essential for efficient muscle regeneration in a mouse model of Duchenne Muscular Dystrophy and its enhanced expression in adult skeletal muscle satellite cells ameliorates the muscle strength in this model. In this experiment, we investigated the impact of mild BMI1 ...
ORGANISM(S): Homo sapiens 
We performed whole blood transcriptome analysis on a total of 70 critically injured patients (Injury Severity Score [ISS] >25) in the hyperacute time period within 2 hours of injury, at 24h and again at 72h. We compared transcriptome findings in 36 critically injured patients with those of 6 patient...
ORGANISM(S): Homo sapiens 
This was a randomised study in terminally anaesthetised female cross-bred Large White pigs. Initially, animals were anaesthetised and instrumented for continuous physiological monitoring and sampling; blood samples were collected upon initiation of the surgery (line-in, T = -150 minutes). Following ...
ORGANISM(S): Sus scrofa 
Patients were recruited between February 2008 and March 2019 through the Activation of Coagulation and Inflammation in Trauma (ACIT-II) study, a prospective platform cohort study evaluating aspects of coagulation and inflammation in trauma patients (NHS REC: 07/Q0603/20). Patients at the Royal Londo...
ORGANISM(S): Homo sapiens 
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