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MetabolomicsCadmium acute exposure induces metabolic and transcriptomic perturbations in human mature adipocytes
Obesity is considered as a major public health concern with strong economic and social burdens. Exposure to pollutants such as heavy metals can contribute to the development of obesity and its associated metabolic disorders, including type 2 diabetes and cardiovascular diseases. Adipose tissue is an...
2023-06-29 | MTBLS4128 | MetaboLights
MetabolomicsMetabolomic analysis of extracellular metabolites from bacterial strains SL8, SL12 and their co-culture under cadmium stress

In this study, bacterial strains 'SL8', 'SL12', and the cocultured 'SL8+SL12' were cultivated in LB medium with or without 100 mg/L cadmium(II) for 48 hours (six replicates per treatment). After centrifugation, extracellular metabolites in the supernatant were extracted using a methanol acetonitr...

2026-05-26 | MTBLS14477 | MetaboLights
MetabolomicsIntegrated transcriptomic and hormonomic insights into cadmium tolerance of a Euglena mutabilis Fungal-Algal-Bacterial (FAB) consortium

Coordinated stress response in E. mutabilis involving early Cd uptake, chloroplast-based detoxification, metabolic buffering via paramylon, suppression of growth-promoting hormones, and community-mediated resilience.

2026-07-14 | MTBLS13259 | MetaboLights
TranscriptomicsEffect of pH on Cadmium Toxicity in Escherichia coli
Metals at high concentrations can exert toxic effects on microorganisms. It has been widely reported that lowering environmental pH reduces effects of cadmium toxicity in bacteria. Understanding the effects of pH-mediated cadmium toxicity on bacteria would be useful for minimizing cadmium toxicity...
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
2008-08-21 | E-GEOD-12373 | biostudies-arrayexpress
MetabolomicsEffects of cadmium exposure on the bumble bee metabolome
Not available
ORGANISM(S): Bombus impatiens 
ST001220 | MetabolomicsWorkbench
TranscriptomicsGlobal gene expression analysis of six cadmium-transformed UROtsa cell isolates
The immortalized human urothelial cell line, UROtsa, was transformed in six parallel cultures with continual passaging in1 µM Cd+2 until the cells were able to attain the ability to form colonies in soft agar and subcutaneous tumors in nude mice. The gene expression profiles between cadmium-transfo...
ORGANISM(S): Homo sapiens 
2011-01-25 | E-GEOD-26828 | biostudies-arrayexpress
MetabolomicsThe effect of pvdA in the cadmium absorption by Pseudomonas umsongensis CR14 through metabolic analysis

In this study, the effects of the Cd-resistant and pyoverdine-producing strain Pseudomonas umsongensis CR14 on Cd stabilization and the mechanisms were investigated. Compared with the control, CR14 markedly reduced the Cd concentration in a Cd-containing solution. The genes pvdA, 4498, 4499, and ...

2025-05-27 | MTBLS12490 | MetaboLights
TranscriptomicsGenetic variation in parthenogenetic collembolans is associated with differences in fitness and cadmium-induced transcriptome responses
Ecotoxicological tests may be biased by the use of laboratory strains that usually contain very limited genetic diversity. It is therefore essential to study how genetic variation influences stress tolerance relevant for toxicity outcomes. To that end we studied sensitivity to cadmium in two distinc...
ORGANISM(S): Folsomia candida 
2012-12-21 | E-GEOD-34167 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat primary hepatocyte in culture after low dose and short incubation time of cadmium in primary
The study was performed using primary rat hepatocyte in culture from 4 adult male Sprague-Dawley rats to investigate the changes in gene expression under low dose (4μM) and short exposure (3hrs) of cadmium chloride. By comparing the gene expression profiles of control and cadmium-treated cells, the...
ORGANISM(S): Rattus norvegicus 
2009-03-07 | E-GEOD-8013 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Sinorhizobium meliloti after exposure to elevated concentrations of the heavy metals cadmium and zinc to analyze stress responses
The stress response of the soil bacterium Sinorhizobium meliloti towards elevated concentrations of the heavy metals cadmium and zinc was analyzed via transcriptional profiling.
ORGANISM(S): Sinorhizobium meliloti 
2008-03-15 | E-MTAB-13 | biostudies-arrayexpress
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