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MetabolomicsThe Sphingolipidome of the model organism Caenorhabditis elegans
Sphingolipids are important lipids and integral members of membranes, where they form small microdomains called lipid rafts. These rafts are enriched in cholesterol and sphingolipids, which influences biophysical properties. Interestingly, the membranes of the biomedical model organism Caenorhabditi...
2024-04-01 | MTBLS963 | MetaboLights
MetabolomicsUntargeted metabolomics analysis of Caenorhabditis elegans
The effects of probiotics on metabolites in Caenorhabditis elegans
2026-07-20 | MTBLS15105 | MetaboLights
MetabolomicsTargeted Metabolome of Caenorhabditis elegans

The effect of Lactiplantibacillus plantarum Q7 on SCFAs in Caenorhabditis elegans

2026-07-20 | MTBLS14034 | MetaboLights
MetabolomicsA metabolomic strategy defines the regulation of lipid content and global metabolism by Δ9 desaturases in Caenorhabditis elegans
Caenorhabditis elegans provides a genetically tractable model organism to investigate the network of genes involved in fat metabolism and how regulation is perturbed to produce the complex phenotype of obesity. C. elegans possess the full range of desaturases, including the delta-9 desaturases expre...
2012-02-14 | MTBLS3 | MetaboLights
MetabolomicsLipidFrag: Improving reliability of in silico fragmentation of lipids and application to the Caenorhabditis elegans lipidome
Lipid identification is a major bottleneck in high-throughput lipidomics studies. We combined the in silico fragmentation tool MetFrag with LipidMaps lipid-class specific classifiers which calculate probabilities for lipid class assignments. The LipidFrag approach was then applied to MS/MS spectra o...
2017-03-09 | MTBLS291 | MetaboLights
MetabolomicsComparison of lipidome profiles of Caenorhabditis elegans—results from an inter-laboratory ring trial

Introduction

Lipidomic profiling allows 100s if not 1000s of lipids in a sample to be detected and quantified. Modern lipidomics techniques are ultra-sensitive assays that enable the discovery of novel biomarkers in a variety of fields and provide new insight in mechanistic investigations. D...
2022-02-21 | MTBLS2016 | MetaboLights
MetabolomicsPolyketide synthase-derived sphingolipids determine microbiota-mediated protection against pathogens in C. elegans

Protection against pathogens is a major function of the gut microbiota. Although bacterial natural products have emerged as crucial components of host-microbiota interactions, their exact role in microbiota-mediated protection is largely unexplored. We addressed this knowledge gap with the nemato...

2025-05-27 | MTBLS8440 | MetaboLights
TranscriptomicsFunction, targets and evolution of Caenorhabditis elegans piRNAs
This SuperSeries is composed of the following subset Series: GSE28617: Function, targets and evolution of Caenorhabditis elegans piRNAs (small RNA-Seq) GSE37432: Function, targets and evolution of Caenorhabditis elegans piRNAs (mRNA) Refer to individual Series
ORGANISM(S): Caenorhabditis elegans 
2012-06-17 | E-GEOD-37433 | biostudies-arrayexpress
TranscriptomicsFormation, regulation and evolution of 3' UTRs in Caenorhabditis elegans
Much of posttranscriptional mRNA regulation occurs through cis-acting sequences in mRNA 3´ untranslated regions (UTRs), which interact with specific proteins and ribonucleoprotein complexes that modulate translation, mRNA stability and subcellular localization. Studies in Caenorhabditis elegans hav...
ORGANISM(S): Caenorhabditis elegans 
2010-12-24 | E-GEOD-24924 | biostudies-arrayexpress
MetabolomicsTargeting phospholipase PLAG-15 promotes healthy aging in C. elegans via lysosomal-related genes
Complex lipid metabolism plays a crucial role in regulating aging. We recently discovered that the phospholipid bis(monoacylglycero)phosphate (BMP) increases in aged human muscles and many mouse tissues. The phospholipase PLA2G15 is reportedly involved in BMP synthesis, however, its specific role in...
2025-06-19 | MTBLS12324 | MetaboLights
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