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TranscriptomicsEffects of PGRMC1 phosphorylation on genome integrity and epigenetics
Progesterone receptor membrane component 1 (PGRMC1) is a protein that has been implicated in cancer biology and poor patient outcomes, which can be over-expressed in cancers, and exist in alternative states of phosphorylation.Here, we show that manipulation of PGRMC1 phosphorylation by mutagenesis r...
ORGANISM(S): Homo sapiens 
2019-12-01 | E-MTAB-8218 | biostudies-arrayexpress
UnknownIntegration of Whole-Genome Sequencing Analysis with Unique Patient-Derived Models Reveals Clinically Relevant Drug Targets in TFCP2 Fusion-Defined Rhabdomyosarcoma.
Not available
S-EPMC12670081 | biostudies-literature
MetabolomicsAntiviral metabolite 3'-Deoxy-3',4'-didehydro-cytidine is detectable in serum and identifies acute viral infections including COVID-19

BACKGROUND: There is a critical need for rapid viral infection diagnostics to enable prompt case identification in pandemic settings and support targeted antimicrobial prescribing.

METHODS: Using untargeted high-resolution liquid chromatography coupled with...

2022-02-10 | MTBLS718 | MetaboLights
TranscriptomicsTranscription profiling of human vascular smooth muscle cells in response to cyclical mechanical strain over a time series of 2, 4 and 24 hours to examine temporal patterns of gene expression in response to strain
Compared the gene expression profiles of human vascular smooth muscle cells in response to cyclical mechanical strain over a time course of 2, 4 and 24 hours to examine temporal pattern of gene expression in response to strain.
ORGANISM(S): Homo sapiens 
2006-07-30 | E-MEXP-569 | biostudies-arrayexpress
UnknownAsynchrony among local communities stabilises ecosystem function of metacommunities.
Not available
S-EPMC6849522 | biostudies-literature
GenomicsEGAS00001000262-sc-20170314 - samples
Whole Genome Sequencing Illumina HiSeq data from 111 men with prostate cancer. Samples were taken from primary tissue obtained at prostatectomy (target sequencing depth 50X) with matched blood control (target sequencing depth 30X). This data is from batches 4 to 6.
EGAD00001003225 | EGA
GenomicsThe Natural History of Human Prostate Cancer - samples
Affymetrix SNP6.0 genotype data for prostate cancer patients
EGAD00010000498 | EGA
GenomicsEGAS00001000262-sc-20160408 - samples
To characterize the subclonal genomic architecture of non-androgen-deprived metastatic prostate cancer, we performed whole-genome sequencing (WGS) of pelvic lymph node metastases and matching noncancerous blood from 10 patients to an average sequencing depth of 55x. The patients are part of PELICAN ...
EGAD00001002002 | EGA
GenomicsEGAS00001000262-sc-20131030 - samples
Whole genome DNA sequencing was used to decrypt the phylogeny of multiple samples from distinct areas of cancer and morphologically normal tissue taken from the prostates of 3 men. For each of three different prostates, multiple tumour samples (4, 5, and 3 depending on the case) and one normal tissu...
EGAD00001000689 | EGA
GenomicsEGAS00001000262-sc-20140722 - samples
To characterize the subclonal genomic architecture of androgen-deprived metastatic prostate cancer, we performed whole-genome sequencing (WGS) of 51 tumours from 10 patients to an average sequencing depth of 55x, including multiple metastases from different anatomic sites in each patient and, in fiv...
EGAD00001000891 | EGA
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