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ProteomicsMulti-omics analysis of serum samples demonstrates reprogramming of organ functions via systemic calcium mobilization and platelet activation in metastatic melanoma patients – proteins from serum samples of melanoma patients with high tumor load
Pathophysiology of cancer-associated syndroms such as cachexia is poorly understood and no routine biomarkers have been established, yet. Using shotgun proteomics, known marker molecules including PMEL, CRP, SAA and CSPG4 were found deregulated in patients with metastatic melanoma. Targeted analysis...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-01-31 | MSV000083385 | MassIVE
ProteomicsMulti-omics analysis of serum samples demonstrates reprogramming of organ functions via systemic calcium mobilization and platelet activation in metastatic melanoma patients - proteins from serum samples of healthy donors
Pathophysiology of cancer-associated syndroms such as cachexia is poorly understood and no routine biomarkers have been established, yet. Using shotgun proteomics, known marker molecules including PMEL, CRP, SAA and CSPG4 were found deregulated in patients with metastatic melanoma. Targeted analysis...
ORGANISM(S): Homo sapiens (Human) 
2016-12-22 | PXD004626 | Pride
Serum analysis Metastatic melanoma Shotgun proteomics Calcium mobilization Mass spectrometry Platelet activation Cachexia Damage signature 
ProteomicsMulti-omics analysis of serum samples demonstrates reprogramming of organ functions via systemic calcium mobilization and platelet activation in metastatic melanoma patients - proteins from serum samples of melanoma patients with low tumor load
Pathophysiology of cancer-associated syndroms such as cachexia is poorly understood and no routine biomarkers have been established, yet. Using shotgun proteomics, known marker molecules including PMEL, CRP, SAA and CSPG4 were found deregulated in patients with metastatic melanoma. Targeted analysis...
ORGANISM(S): Homo sapiens (Human) 
2016-12-22 | PXD004625 | Pride
Serum analysis Metastatic melanoma Shotgun proteomics Calcium mobilization Mass spectrometry Platelet activation Cachexia Damage signature 
ProteomicsMulti-omics analysis of serum samples demonstrates reprogramming of organ functions via systemic calcium mobilization and platelet activation in metastatic melanoma patients – proteins from serum samples of melanoma patients with high tumor load
Pathophysiology of cancer-associated syndroms such as cachexia is poorly understood and no routine biomarkers have been established, yet. Using shotgun proteomics, known marker molecules including PMEL, CRP, SAA and CSPG4 were found deregulated in patients with metastatic melanoma. Targeted analysis...
ORGANISM(S): Homo sapiens (Human) 
2016-12-22 | PXD004624 | Pride
Serum analysis Metastatic melanoma Shotgun proteomics Calcium mobilization Mass spectrometry Platelet activation Cachexia Damage signature 
ProteomicsProteomic Analyses Role of Calcium in Radicle Elongation during Rice Seed Germination
our works provide evidences that radicle elongation will be hindered in presence of calcium ion mobilization inhibitors during rice seed germination.
ORGANISM(S): Oryza sativa (Rice) 
2020-03-25 | PXD010578 | Pride
Rice Proteomics Radicle elongation Calcium Seed germination 
ProteomicsCombinatory shotgun proteomics and shotgun eicosadomics study of platelets activated by calcium mobilization - secreted proteins of platelets stimulated for 3h with ionomycin
Platelets are involved in relevant physiological and pathophysiological processes such as hemostasis and tumor progression. These anucleate blood particles exert their functions essentially by releasing effector molecules such as proteins from intracellular granules and by generating and secreting s...
ORGANISM(S): Homo sapiens (Human) 
2022-03-01 | PXD005054 | Pride
Shotgun proteomics and eicosadomics Secretomes Human platelets Lysates Mass spectrometry Activation by calcium mobilization 
GenomicsProstate cancer cell-platelet bidirectional signaling promotes calcium mobilization, invasion and apoptotic resistance via distinct receptor-ligand pairs
Prostate cancer cell-platelet bidirectional signaling promotes calcium mobilization, invasion and apoptotic resistance via distinct receptor-ligand pairs
PRJNA896214 | ENA
UnknownIntracellular Calcium Mobilization Is Required for Sonic Hedgehog Signaling.
Not available
S-EPMC6007892 | biostudies-literature
UnknownCadmium induces transcription independently of intracellular calcium mobilization.
Not available
S-EPMC3111418 | biostudies-literature
UnknownDematin Regulates Calcium Mobilization, Thrombosis, and Early Akt Activation in Platelets.
Not available
S-EPMC10251785 | biostudies-literature
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