Calcium-signalling

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Instrument Platform

Illumina NovaSeq 6000 (26)
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With L-glutamine supplemented with 10% fetal bovine serum (FBS) (Gibco) and 1% penicillin-streptomycin (10,000 units/mL penicillin and 10 mg/mL streptomycin) (Gibco). (1)
STAR (1)
Single Cell/Low Input RNA Library Prep Kit for Illumina (#E6420S, New England Biolabs) (1)
RNA Micro Kit (Qiagen). (1)
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Publication Date

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UNIPROT ID/AC

P10687 (3)
Q9JID2 (3)
Q99PS2 (2)
Q03114 (2)
Q9UD71 (2)
Q08999 (2)
P11802 (2)
Q01094 (2)
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A0A3B6D6K8_WHEAT (2)
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4565.Traes_5BL_EB5679CA8.1 (2)
A0A3B6IS21_WHEAT (2)
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4565.Traes_6BL_722B84F24.1 (2)
A0A3B6LM83_WHEAT (2)
4565.Traes_3DS_A379914C4.1 (2)
A0A3B6KHB8_WHEAT (2)
4565.Traes_7DL_F8AF46FFE.1 (2)
A0A3B6LVZ1_WHEAT (2)
4565.Traes_3DL_116693163.1 (2)
4565.Traes_3AL_367B04E24.1 (2)
P50148 (1)
P19174 (1)
P0DP23 (1)
P04049 (1)
Q02750 (1)
P28482 (1)

CHEBI ID

CHEBI:16828 (12)
CHEBI:30769 (12)
CHEBI:16750 (11)
CHEBI:6650 (11)
CHEBI:17568 (11)
CHEBI:18050 (11)
CHEBI:16015 (11)
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CHEBI:16027 (10)
CHEBI:15741 (10)
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CHEBI:29108 (7)
CHEBI:17287 (5)
CHEBI:16761 (5)
CHEBI:15846 (4)
CHEBI:47867 (2)
CHEBI:17489 (2)
CHEBI:16595 (2)
CHEBI:16541 (2)
CHEBI:5656 (1)
CHEBI:39124 (1)
CHEBI:26689 (1)
CHEBI:29101 (1)
CHEBI:16004 (1)
CHEBI:17138 (1)
CHEBI:15361 (1)
CHEBI:16908 (1)
CHEBI:18021 (1)
CHEBI:17234 (1)

Metabolite Name

Inosine (19)
Guanosine (18)
Adenine (17)
Uridine (17)
Uracil (16)
Taurine (16)
Cytidine (16)
Creatine (16)
Hypoxanthine (16)
Xanthine (15)
L-Leucine (15)
L-Alanine (14)
Betaine (14)
Adenosine (14)
L-Glutamine (14)
L-Tyrosine (14)
Ornithine (13)
Choline (13)
Creatinine (13)
L-Phenylalanine (13)
L-Tryptophan (12)
Deoxyguanosine (12)
L-Valine (12)
L-Isoleucine (12)
Glutathione (11)
L-Proline (11)
L-Histidine (11)
Cholic acid (11)
Deoxyinosine (11)
Thymine (10)

First Public Date

2014 (17)
2025 (16)
2024 (15)
2023 (9)
2022 (9)
2026 (8)
2021 (8)
2015 (6)
2020 (4)
2017 (4)
2018 (3)
2019 (1)
2016 (1)

Modelling Approach

Ordinary differential equation model (13)

Lab affiliation

Department of Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, Geneva, CH-1211 Switzerland (2)
The University of Melbourne (2)
Synapse Proteomics Group, Children's Medical Research Institute, University of Sydney, Westmead, New South Wales, Australia (1)
Department of Women and Children’s Health, Science for Life Laboratory, Karolinska Institutet, Stockholm, Sweden (1)
Beijing Key Laboratory of Gene Resource and Molecular Development, College of Life Sciences, Beijing Normal University, Beijing China (1)
Centre for MND Research, Department of Biomedical Sciences, Macquarie University, North Ryde, NSW, 2109 Australia (1)
Head, Angiogenesis and Tumor Microenvironment Lab The Swiss Institute for Experimental Cancer Research (ISREC) School of Life Sciences Ecole Polytechnique Fédérale de Lausanne (EPFL) (Swiss Federal Institute of Technology, Lausanne, Switzerland) (1)
The Francis Crick Institute Signalling in Apicomplexan Parasites Laboratory London NW1 1AT United Kingdom (1)
Dipartimento di Medicina Veterinaria, Università degli Studi di Milano, Milano; Italy (1)
Department of Life Sciences, University of Siena, Italy (1)
Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom (1)
The Francis Crick Institute 1 Midland Road London NW1 1AT UK (1)
Head Of Proteomics STP, Francis Crick Institute, London (1)
Asst. Professor (Department of Biotechnology), National Institute of Pharmaceutical Education & Research (NIPER), Sector-67, S.A.S. Nagar, Mohali-160062, Punjab. (India) (1)
Malaria Parasite Biology and Vaccines, Department of Parasites and Insect Vectors, Institute Pastuer, 25-28 Rue du Docteur Roux 75015, Paris France (1)
Department of Molecular Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, Switzerland (1)
HUN-REN–SU System Pharmacology Research Group, Department of Pharmacology and Pharmacotherapy, Semmelweis University, Pharmahungary Group, Záhony utca 7, 1031 Budapest, Hungary (1)
School of Medical Sciences, Faculty of Medicine and Healthy, University of Sydney, Sydney, Australia. (1)
Department of Biochemistry and Functional Proteomics, Institute of Biology II, Faculty of Biology and Signalling Research Centres BIOSS and CIBSS, University of Freiburg, 79104 Freiburg im Breisgau, Germany (1)
Institute of Clinical Physiology, National Research Council, 56124 Pisa, Italy. (1)
Centre for Cancer Research, Hudson Institute of Medical Research, Clayton, Australia. Department of Medicine, School of Clinical Sciences, Monash University, Clayton, Australia. 2 Department of Medicine, School of Clinical Sciences, Monash University, Clayton, Australia. 3 Monash Proteomics and Metabolomics Platform, Clinical Proteomics Node, School of Clinical Sciences, Monash University, Clayton, Australia (1)
Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada (1)
Laboratory of Cell Biophysics Nencki Institute of Experimental Biology PAS Warsaw, Poland (1)
Max Planck Institute for Multidisciplinary Sciences (1)
Department of Biochemistry and Chemistry, Research Centre for Extracellular Vesicles, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC 3086, Australia (1)
College of Medicine, Department of Medical Sciences, University of Sharjah, Sharjah, UAE Center of Excellence of Precision Medicine, Sharjah Institute for Medical Research, Sharjah, UAE Research Institute of Medical and Research Sciences, Sharjah, UAE (1)
Synapse Proteomics Group Children's Medical Research Institute University of Sydney (1)
The Hong Kong Polytechnic University (1)
the University of Sydney (1)
Institut de Génomique Fonctionnelle, Université de Montpellier, CNRS, INSERM, Montpellier, France (1)

IsPrivate

False (13)

Classification

fungi (1)

Modification

4-tetrahydrothiazine-3-carboxylic acid (1)

Study type

Transcription profiling by array (1346)
RNA-seq of coding RNA (197)
ChIP-seq (91)
Unknown experiment type (41)
Comparative genomic hybridization by array (18)
ChIP-chip by tiling array (14)
RNA-seq of non coding RNA (14)
Methylation profiling by array (10)
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Cell line - High-throughput sequencing (8)
Other (6)
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Animal - One-color microarray (4)
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Release Date

2013 (293)
2015 (259)
2014 (235)
2012 (233)
2010 (226)
2011 (190)
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2008 (169)
2009 (114)
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2007 (82)
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2004 (7)
2003 (3)
2002 (3)
2001 (3)
2000 (1)
1999 (1)
1998 (1)

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Tetrandrine regulates NAADP-mediated calcium signalling 1 through a novel LIMP-2-dependent, sphingosine-mediated mechanism.

Tetrandrine (Tet) is an highly potent inhibitor of Ebola virus replication by blocking NAADP51 dependent calcium release through endolysosomal two-pore channels (TPCs) and a moderately potent anti-tumor agent. Using a clickable, photoaffinity probe of Tet, we identified lysosomal integral membrane p...

2025-05-23 | MTBLS12492 | MetaboLights

Tetrandrine regulates NAADP-mediated calcium signalling through a novel LIMP-2-dependent, sphingosine-mediated mechanism

PRJNA876411 | ENA

A positive feedback loop mediates crosstalk between calcium, cyclic nucleotide and lipid signaling in Toxoplasma gondii.

Fundamental processes of obligate intracellular parasites, such as Plasmodium falciparum and Toxoplasma gondii are controlled by a set of plant-like calcium dependent kinases (CDPKs), the conserved cAMP- and cGMP-dependent protein kinases (PKA and PKG), second messengers and lipid signalling. While ...

ORGANISM(S): Homo sapiens (Human) Toxoplasma gondii RH

2022-10-17 | PXD030057 | Pride

Regulation of mitochondrial Ca2+ uniporter expression and calcium signalling by lncRNA Tug1 in cardiomyocytes

PRJNA996608 | ENA

Rhomboid protease RHBDL2 is a calcium-activated suppressor of EGFR signalling in keratinocytes.

Signalling via the epidermal growth factor receptor (EGFR) is indispensable for morphogenesis and tissue homeostasis. It is activated by extracellular ligands, typically released from transmembrane precursors by proteolysis. Ligand shedding activity is provided by the conserved rhomboid intramembran...

ORGANISM(S): Homo sapiens (Human)

2026-09-28 | PXD014766 | Pride

Tetrandrine regulates NAADP-mediated calcium signalling through a novel LIMP-2-dependent, sphingosine-mediated mechanism

Tetrandrine (Tet) is a highly potent inhibitor of Ebola virus replication by blocking NAADP-dependent calcium release through endolysosomal two-pore channels (TPCs) and is a moderately potent anti-tumor agent. Using a clickable, photoaffinity probe of Tet, we identified lysosomal integral membrane p...

ORGANISM(S): Homo sapiens

2023-03-04 | GSE212648 | GEO

Modulation of calcium signalling on demand to decipher the molecular mechanisms of primary aldosteronism

PRJNA1188188 | ENA

Towards the Physics of Calcium Signalling in Plants.

Not available

S-EPMC4844391 | biostudies-literature

Kummer2000 - Oscillations in Calcium Signalling

Kummer2000 - Oscillations in Calcium Signalling Simplified (3-variable) calcium oscillation model Kummer et al. (2000) Biophys. J. 79, 1188-1195 This model is defined in a small compartment with low concentrations. You can run it first with the LSODA ODE solver and then with the Gillespie M...

2024-09-02 | BIOMD0000000329 | BioModels

Calcium Signalling in Medulloblastoma: An In Silico Analysis of the Expression of Calcium Regulating Genes in Patient Samples.

Not available

S-EPMC8468187 | biostudies-literature

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