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TranscriptomicsEgress of mature murine regulatory T cells from the thymus requires RelA
The mechanism of egress of mature regulatory T cells (Tregs) from the thymus to the periphery remains enigmatic, as does the nature of those factors expressed in the thymic environment. Here, we examined the fate of thymic Tregs in TNFα/RelA double-knockout (TA-KO) mice, because TA-KO mice retain a...
ORGANISM(S): Mus musculus 
2015-03-04 | E-GEOD-64191 | biostudies-arrayexpress
TranscriptomicsSingle-cell RNA sequencing of a 3D blood-brain-barrier model perfused with P. falciparum-infected red blood cells and egress products
This dataset consists of two individual sample-multiplexing (MULTI-seq) single-cell RNA sequencing experiments, MB10x01 and MB10x02. Single-cell RNA sequencing (10X Genomics) analyses were performed on a microfluidic 3D in vitro blood-brain-barrier model (containing primary human brain microvascular...
ORGANISM(S): Homo sapiens 
2025-06-25 | E-MTAB-14463 | biostudies-arrayexpress
ProteomicsNovel asymmetric isopeptide bond steers directional genomic RNA egress from icosahedral virus
How essential asymmetries are built into icosahedral virus to facilitate directional genome egress is unknown. Here we capture the structure and dynamics of disassembly intermediates of an icosahedral virus. We reveal localized RNA density poised for release beneath 5-fold axes on one half of the vi...
ORGANISM(S): Turnip crinkle virus 
2025-11-06 | PXD067878 | Pride
Turnip crinkle virus Hdxms Rna egress Asymmetry Isopeptide bond 
GenomicsMevalonate metabolism-dependent protein geranylgeranylation regulates thymocyte egress
Mevalonate metabolism-dependent protein geranylgeranylation regulates thymocyte egress
PRJNA558354 | ENA
TranscriptomicsBulk RNA-seq of HBMEC, iBMEC-like cells, and ETS-iBMEC in Response to Plasmodium falciparum Egress Products
This dataset comprises bulk RNA sequencing (RNA-seq) data generated from primary human brain microvascular endothelial cells (HBMECs), induced pluripotent stem cell (iPSC)-derived iBMEC-like cells, and ETS-transcription factor-guided iPSC-derived endothelial cells (ETS-iBMEC). Cells were cultured as...
ORGANISM(S): Homo sapiens 
2026-03-05 | E-MTAB-14937 | biostudies-arrayexpress
ProteomicsP.Falciparum gametocyte egress secretome
Proteins released in the cultured medium of eritrocytes infected by Plasmodium Falciparum at the moment of gametocyte egress
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Plasmodium Falciparum 3d7 (ncbitaxon:36329) 
2020-12-24 | MSV000086635 | MassIVE
GenomicsRNA-seq of IMR90 senescence with CCF nuclear egress inhibition
RNA-seq of IMR90 senescence with CCF nuclear egress inhibition
PRJNA1136149 | ENA
ProteomicsHCMV-NEC analysis - Proteomic analysis of the multimeric nuclear egress complex of human cytomegalovirus
Herpesviral capsids are assembled in the host cell nucleus before being translocated to the cytoplasm where they undergo further maturation. The crossing of nuclear envelope represents a major event that requires formation of the nuclear egress complex (NEC). We investigated the protein composition ...
ORGANISM(S): Homo sapiens (Human) Human cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5) 
2014-06-30 | PXD000536 | Pride
Nuclear egress complex Coimmunoprecipitation Nanolc-msms Human cytomegalovirus 
ProteomicsProteomic analyses identified distinct types of vesicles essential for egress of Plasmodium falciparum gametocytes from red blood cells
Transmission of malaria parasites to the mosquito is mediated by sexual precursor cells, the gametocytes. Upon entering the mosquito midgut, the gametocytes egress from the enveloping erythrocyte while passing through gametogenesis. Egress follows an inside-out mode during which the membrane of the ...
ORGANISM(S): Plasmodium Falciparum 
2024-01-25 | PXD039679 | JPOST Repository
ProteomicsMyosin-9 is required for lysosome-mediated nonlytic reovirus egress
Mammalian orthoreoviruses (reoviruses) are nonenveloped, double-stranded RNA viruses that assemble progeny particles in cytoplasmic viral factories (VFs) and exit some types of cells using a nonlytic release mechanism. In human brain microvascular endothelial cells (HBMECs), progeny reovirus virions...
ORGANISM(S): Homo sapiens (Human) Orthoreovirus 
2025-10-10 | PXD068971 | Pride
Reovirus  virus egress  myosin-9  proteomics  imaging 
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