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ProteomicsCRISPR targeting of FOXL2 c.402C>G mutation reduces malignant phenotype in granulosa tumor cells and identifies anti-tumoral compounds
FOXL2 is a transcription factor that plays a key role in sex determination, ovary development and maintenance. Mutations related to this gene have been described in syndromes involving premature ovarian failure and granulosa cell tumors. This kind of rare cancer (less than 5% of diagnosed ovarian ca...
ORGANISM(S): Homo sapiens (Human) 
2025-03-15 | PXD053682 | Pride
Tmt Rare cancer Crispr Granulosa cell tumor Proteomics Foxl2 
UnknownMedical nutrition therapy for gestational diabetes mellitus based on Mediterranean Diet principles: a subanalysis of the St Carlos GDM Prevention Study.
Not available
S-EPMC6202993 | biostudies-literature
UnknownBody composition as a complementary tool for detection of metabolic syndrome 6 years postpartum: a St. Carlos Cohort follow-up.
Not available
S-EPMC12614464 | biostudies-literature
UnknownTherapeutic Response After Immunosuppressive Drug Prescription in Non-infectious Uveitis: A Survival Analysis.
Not available
S-EPMC9834496 | biostudies-literature
UnknownA Mediterranean diet with additional extra virgin olive oil and pistachios reduces the incidence of gestational diabetes mellitus (GDM): A randomized controlled trial: The St. Carlos GDM prevention study.
Not available
S-EPMC5648128 | biostudies-literature
UnknownBenefits of Adhering to a Mediterranean Diet Supplemented with Extra Virgin Olive Oil and Pistachios in Pregnancy on the Health of Offspring at 2 Years of Age. Results of the San Carlos Gestational Diabetes Mellitus Prevention Study.
Not available
S-EPMC7290358 | biostudies-literature
UnknownThe Consumption of Food-Based Iodine in the Immediate Pre-Pregnancy Period in Madrid Is Insufficient. San Carlos and Pregnancy Cohort Study.
Not available
S-EPMC8707458 | biostudies-literature
UnknownEffectiveness of Following Mediterranean Diet Recommendations in the Real World in the Incidence of Gestational Diabetes Mellitus (GDM) and Adverse Maternal-Foetal Outcomes: A Prospective, Universal, Interventional Study with a Single Group. The St Carlos Study.
Not available
S-EPMC6627921 | biostudies-literature
UnknownTCF7L2 rs7903146 polymorphism modulates the association between adherence to a Mediterranean diet and the risk of gestational diabetes mellitus.
Not available
S-EPMC7718167 | biostudies-literature
UnknownAn Early Mediterranean-Based Nutritional Intervention during Pregnancy Reduces Metabolic Syndrome and Glucose Dysregulation Rates at 3 Years Postpartum.
Not available
S-EPMC10383706 | biostudies-literature
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